2-Oxazolamine, N-(dicyclopropylmethyl)-4,5-dihydro-, phosphate (1:1)
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2-Oxazolamine, N-(dicyclopropylmethyl)-4,5-dihydro-, phosphate (1:1)
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CAS No:
85409-38-7
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Formula:
C10H16N2O.H3O4P
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Chemical Name:
2-Oxazolamine, N-(dicyclopropylmethyl)-4,5-dihydro-, phosphate (1:1)
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Synonyms:
2-Oxazolamine,N-(dicyclopropylmethyl)-4,5-dihydro-,phosphate (1:1);S 3341-3;Rilmenidine phosphate
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CAS No:
Description
White or almost white powder.
Oxazole derivative that acts as an agonist for ALPHA-2 ADRENERGIC RECEPTORS and IMIDAZOLINE RECEPTORS. It is used in the treatment of HYPERTENSION.
2-Oxazolamine, N-(dicyclopropylmethyl)-4,5-dihydro-, phosphate (1:1) Basic Attributes
278.24
278.103149
287-106-2
59QD64Q32M
DTXSID50234616
2934999090
Characteristics
111
0.04870
609.1°C at 760 mmHg
322.1ºC
Freely soluble in water, slightly soluble in alcohol, practically insoluble in methylene chloride.
Safety Information
P201, P260, P261, P263, P264, P270, P271, P273, P301+P310, P301+P312, P304+P312, P304+P340, P308+P313, P312, P314, P321, P330, P391, P405, P501
H301
|Danger|H301 (50%): Toxic if swallowed [Danger Acute toxicity, oral]|P201, P260, P261, P263, P264, P270, P271, P273, P301+P310, P301+P312, P304+P312, P304+P340, P308+P313, P312, P314, P321, P330, P391, P405, and P501|Aggregated GHS information provided by 5 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Compounds that bind to and activate ADRENERGIC ALPHA-2 RECEPTORS. (See all compounds classified as Adrenergic alpha-2 Receptor Agonists.)|Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)|Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here. (See all compounds classified as Sympatholytics.)
2-(N-(dicyclopropylmethyl)amino)oxazoline
2-Oxazolamine, N-(dicyclopropylmethyl)-4,5-dihydro-, phosphate (1:1) Use and Manufacturing
Antihypertensive
Computed Properties
Molecular Weight:278.24
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:278.10315871
Monoisotopic Mass:278.10315871
Topological Polar Surface Area:111
Heavy Atom Count:18
Complexity:269
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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2-Oxazolamine, N-(dicyclopropylmethyl)-4,5-dihydro-, phosphate (1:1)
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