SCH900776
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SCH900776
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CAS No:
891494-63-6
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Formula:
C15H18BrN7
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Chemical Name:
SCH900776
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Synonyms:
6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3R)-3-piperidinylpyrazolo[1,5-a]pyrimidin-7-amine;MK-8776 (SCH 900776);SCH 900776 (MK-8776);SCH900776(R);6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-((R)-piperidin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine;SCH 900776, >=98%;(R)-6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine
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CAS No:
Description
SCH900776 is a potent, selective and oral inhibitor of checkpoint kinase1 (Chk1) with an IC50 of 3 nM. It shows 50- and 500-fold selectivity over CDK2 andChk2, respectively.
SCH900776 Use and Manufacturing
This compound acts as a novel Chk1 inhibitor acting as an anticancer agent.
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