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LDN212854

LDN212854 structure

CAS No:
1432597-26-6
Formula:
C25H22N6
Chemical Name:
LDN212854
Synonyms:
LDN212854;5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyriMidin-3-yl]quinoline;Quinoline, 5-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-;BMP Inhibitor III;5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline LDN 212854;LDN 212854 5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;LDN-212854, >=98%
Categories:
Biochemical Engineering > Inhibitors

Description

LDN-212854 is a potent and selective BMP receptor inhibitor with IC50 of 1.3 nM for ALK2, about 2-, 66-, 1641-, and 7135-fold selectivity over ALK1, ALK3, ALK4, and ALK5, respectively.

LDN212854 Basic Attributes

Molecular Weight：

406.48238

Exact Mass：

406.191

EC Number：

-0

Characteristics

PSA：

58.4

XLogP3：

3.3

Appearance：

white to beige

Water Solubility：

DMSO: soluble1mg/mL, clear (warmed)

Storage Conditions：

2-8°C

Safety Information

Packing level：

Ⅲ

Transport codes：

2811

wgk germany：

hazard class code：

Marks：

Precautionary statement(s)：

P264, P270, P301+P310, P321, P330, P405, P501

Hazard Statements：

H301

Drug Information

MeSH Entry Terms：

LDN-212854

Computed Properties

Molecular Weight:406.5
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:406.19059473
Monoisotopic Mass:406.19059473
Topological Polar Surface Area:58.4
Heavy Atom Count:31
Complexity:587
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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LDN-212854

CAS No.: 1432597-26-6

Content: 99.00%

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