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Home > Encyclopedia > ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE

ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE

ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE structure

ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE 

structure
  • CAS No:

    105565-55-7

  • Formula:

    C18H23ClF2N4O

  • Chemical Name:

    ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE

  • Synonyms:

    ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE;BMY 14802 HYDROCHLORIDE;BMY14802HyClHCl;BMS-181100;BMY-14802-1;α-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanolhydrochloride

ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE Basic Attributes

384.85

384.153

Characteristics

52.5

3.19550

520.8ºC at 760mmHg

268.8ºC

Desiccate at RT

1.13E-11mmHg at 25°C

Drug Information

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)

alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol

ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE Use and Manufacturing

Potent sigma receptor antagonist (IC 50 = 112 nM) with modest to weak affinity for 5-HT 1A and α 1 receptors. Antipsychotic following oral administration and acts via indirect modulation of central dopaminergic systems.

Computed Properties

Molecular Weight:384.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:384.1528454
Monoisotopic Mass:384.1528454
Topological Polar Surface Area:52.5
Heavy Atom Count:26
Complexity:379
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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