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Centaureidin

Centaureidin structure

Centaureidin 

structure
  • CAS No:

    17313-52-9

  • Formula:

    C18H16O8

  • Chemical Name:

    Centaureidin

  • Synonyms:

    4H-1-Benzopyran-4-one,5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimethoxy-;Flavone,3′,5,7-trihydroxy-3,4′,6-trimethoxy-;Centaureidin;5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimethoxy-4H-1-benzopyran-4-one;Quercetagetin 3,4′,6-trimethyl ether;5,7,3′-Trihydroxy-3,6,4′-trimethoxyflavone;NSC 106969;Desmethoxycentaureidine

Description

ChEBI: A trihydroxyflavone that consists of quercetagetin in which the hydroxy groups at positions 3, 6 and 4' have been replaced by methoxy groups. It has been isolated from Eremophila mitchellii and Athroisma proteiforme.


Centaureidin is a trihydroxyflavone that consists of quercetagetin in which the hydroxy groups at positions 3, 6 and 4' have been replaced by methoxy groups. It has been isolated from Eremophila mitchellii and Athroisma proteiforme. It has a role as a cyclooxygenase 1 inhibitor, a cyclooxygenase 2 inhibitor, an antineoplastic agent and a plant metabolite. It is a trihydroxyflavone and a trimethoxyflavone.

Centaureidin Basic Attributes

360.316

360.31

548R7290J9

106969

DTXSID50169530

2914509090

Characteristics

115

2.60260

1.54±0.1 g/cm3 (20 ºC 760 Torr)

203 °C

649.9ºC at 760mmHg

239.1ºC

1.639

Drug Information

5,7,3'-trihydroxy-3,6,4'-trimethoxyflavone

Centaureidin Use and Manufacturing

Polyketides [PK] -> Flavonoids [PK12] -> Flavones and Flavonols [PK1211]

Computed Properties

Molecular Weight:360.3
XLogP3:2.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:360.08451746
Monoisotopic Mass:360.08451746
Topological Polar Surface Area:115
Heavy Atom Count:26
Complexity:561
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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