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Elisartan

Elisartan structure

Elisartan 

structure
  • CAS No:

    149968-26-3

  • Formula:

    C27H29ClN6O5

  • Chemical Name:

    Elisartan

  • Synonyms:

    1H-Imidazole-5-carboxylic acid,2-butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-,1-[(ethoxycarbonyl)oxy]ethyl ester;1H-Imidazole-5-carboxylic acid,2-butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-,1-[(ethoxycarbonyl)oxy]ethyl ester;HN 65021;Elisartan;158682-68-9

Elisartan Basic Attributes

553.016

553.01

Characteristics

134

6.5

1.35±0.1 g/cm3(Predicted)

745.0±70.0 °C(Predicted)

Drug Information

Agents that antagonize ANGIOTENSIN II TYPE 1 RECEPTOR. Included are ANGIOTENSIN II analogs such as SARALASIN and biphenylimidazoles such as LOSARTAN. Some are used as ANTIHYPERTENSIVE AGENTS. (See all compounds classified as Angiotensin II Type 1 Receptor Blockers.)

1-(ethoxycarbonyloxy)ethyl 2-butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylate

Computed Properties

Molecular Weight:553.0
XLogP3:6.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:14
Exact Mass:552.1887957
Monoisotopic Mass:552.1887957
Topological Polar Surface Area:134
Heavy Atom Count:39
Complexity:788
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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