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Belotecan

Belotecan structure

Belotecan 

structure
  • CAS No:

    256411-32-2

  • Formula:

    C25H27N3O4

  • Chemical Name:

    Belotecan

  • Synonyms:

    1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-,(4S)-;(4S)-4-Ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;Belotecan;Camtobell;7-[2-(N-Isopropylamino)ethyl]-(20S)-camptothecin

Description

Belotecan is a pyranoindolizinoquinoline.|Belotecan has been investigated for the treatment of Epithelial Ovarian Cancer.

Belotecan Basic Attributes

433.50000

433.50

27Z82M2G1N

DTXSID60180332

L - Antineoplastic and immunomodulating agents

Characteristics

93.45000

3.01100

1.36g/cm3

772.4ºC at 760mmHg

420.9ºC

1.678

4.21E-25mmHg at 25°C

Drug Information

Compounds that inhibit the activity of DNA TOPOISOMERASE I. (See all compounds classified as Topoisomerase I Inhibitors.)

7-(2-(N-isopropylamino)ethyl)camptothecin

Computed Properties

Molecular Weight:433.5
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:433.20015635
Monoisotopic Mass:433.20015635
Topological Polar Surface Area:91.8
Heavy Atom Count:32
Complexity:865
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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