1,1,1,2,2,3,4,5,5,5-Decafluoropentane

252.05300

252.05

420-640-8|604-080-3

MC53096Z2M

Clear, colorless liquid|Nonflammable liquid|Colorless liquid

0.00000

3.42250

Clear colorless liquid

1.600 g/cm³

-80ºC

53.6ºC

>125ºC

n20/D 1.3

In water, 140 ppm at 25 °C

Keep container tightly closed in a dry and well-ventilated place. /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/

0.297 atm (225.72 mm Hg) at 25 °C

Henry's Law constant = 5.34X10-1 atm-cu m/mol at 25 °C (est)

Global Warming Potential (GWP): Chemical: HFC-43-10mee; GWP: 1,640 (100-Year Time Horizon)|Ozone depletion is zero; global warming potential is low|Critical volume: 0.433 L/mol|Specific heat: 1.13 kJ/kg-deg C at 20 °C|Hydroxyl radical reaction rate constant = 3.40X10-15 cu cm/molec-sec at 25 °C

129.7 kJ/kg at 55 °C (boiling point)

Critical temperature: 181 °C; critical pressure: 2288 kPa

1

R36/37/38

S26-S37/39

RZ9885000

Xi

Stable under recommended storage conditions. /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/

SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.|Product: Offer surplus and non-recyclable solutions to a licensed disposal company; Contaminated packaging: Dispose of as unused product. /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/

Incompatible materials: Strong oxidizing agents, Alkaline earth metals, Strong bases /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/

Danish EPA; Survey of selected fluorinated green-house gases (2015)[Available from, as of March 3, 2016: http://eng.mst.dk/]

|Warning|H315 (26.15%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 130 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H412 (100%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]|P273, and P501|Aggregated GHS information provided by 31 companies from 2 notifications to the ECHA C&L Inventory.|H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]

Eye/face protection: Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/|Skin protection: Handle with gloves. /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/|Body Protection: Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/|Respiratory protection: Respiratory protection not required. For nuisance exposures use type OV/AG (US) or type ABEK (EU EN 14387) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/|Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary. /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/

ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Avoid breathing vapors, mist or gas. Ensure adequate ventilation; Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided; Methods and materials for containment and cleaning up: Keep in suitable, closed containers for disposal. /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/

Precautions for safe handling: Normal measures for preventive fire protection. /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/|Appropriate engineering controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/|Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. /1,1,1,2,3,4,4,5,5,5-Decafluoropentane/

RURAL/REMOTE: We report in situ atmospheric measurements of hydrofluorocarbon HFC-43-10mee (C5H2F10; 1,1,1,2,2,3,4,5,5,5-decafluoropentane) from seven observatories at various latitudes, together with measurements of archived air samples and recent Antarctic flask air samples. The global mean tropospheric abundance was 0.21 +/- 0.05 ppt (parts per trillion, dry air mole fraction) in 2012, rising from 0.04 +/-0.03 ppt in 2000. We combine the measurements with a model and an inverse method to estimate rising global emissions-from 0.43 +/- 0.34 Gg/yr in 2000 to 1.13 +/-0.31 Gg/yr in 2012 (approximately 1.9 Tg CO2-eq/yr based on a 100 year global warming potential of 1660). HFC-43-10mee - a cleaning solvent used in the electronics industry - is currently a minor contributor to global radiative forcing relative to total HFCs; however, our calculated emissions highlight a significant difference from the available reported figures and projected estimates(1).

2,3-Dihydroperfluoropentane is listed as an ingredient in three commercial/institutional aerosol cleaning products at 0-60%(1).

IDENTIFICATION AND USE: 2H,3H-decafluoropentane is a clear, colorless liquid. It is a new fluorocarbon alternative with no known ozone-depleting potential, designed for use in cleaning circuit boards. HUMAN EXPOSURE AND TOXICITY: There are no data available. ANIMAL STUDIES: The subchronic toxicity, neurotoxicity, and teratogenicity were evaluated by exposing male and female rats to 0, 500, 2,000 or 3,500 ppm /by inhalation/ for 6 hr/d, 5d/wk for 13 weeks (or gestation days 7-16). Parameters evaluated included body weight, food consumption, functional observational battery, motor activity, clinical pathology, standard pathology, and neuropathology. Additional short-term exposures were conducted at 1,000, 1,500, 2,500, and 3,000 ppm to better define NOEL for convulsive effects. Convulsions occurred during exposure at 3,500 ppm and to a minimal extent at 2,000 ppm. Convulsions did not occur at 1,000 ppm or below. Motor activity was reduced at 3,500 ppm. Effects on serum albumin and urinalysis parameters occurred at 3,500 ppm. No compound-related effects on body weight, food consumption, hematology parameters, pathology parameters, or neuropathology endpoints were detected. Pregnant females exposed to 2,000 or 3,500 ppm had clinical signs of toxicity and lower body weight. Fetal body weight was lower at 3,500 ppm.

LD50 Rat oral >5000 mg/kg|LD50 Rabbit skin >5000 mg/kg

2,3-Dihydroperfluoropentane's production and use as a precision cleaning solvent for electronics(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 7800(SRC), determined from a structure estimation method(2), indicates that 2,3-dihydroperfluoropentane is expected to be immobile in soil(SRC). Volatilization of 2,3-dihydroperfluoropentane from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 0.53 atm-cu m/mole(SRC), based upon its vapor pressure, 225.72 mm Hg(3), and water solubility, 140 mg/L(3). However, adsorption to soil is expected to attenuate volatilization(SRC). 2,3-Dihydroperfluoropentane is expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(3). Biodegradation data in soil were not available(SRC, 2016).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 7800(SRC), determined from a structure estimation method(2), indicates that 2,3-dihydroperfluoropentane is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 0.53 atm-cu m/mole(SRC), derived from its vapor pressure, 225.72 mm Hg(4), and water solubility, 140 mg/L(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 4.6 hours and 6.3 days, respectively(SRC). However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The estimated volatilization half-life from a model pond is 62 days if adsorption is considered(5). 2,3-Dihydroperfluoropentane is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(3). According to a classification scheme(6), an estimated BCF of 160(SRC), from an estimated log Kow of 3.84(2) and a regression-derived equation(2), suggests the potential for bioconcentration in aquatic organisms is high(SRC). Biodegradation data in water were not available(SRC, 2016).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 2,3-dihydroperfluoropentane, which has a vapor pressure of 225.7 mm Hg at 25 °C(2), is expected to exist solely as a gas in the ambient atmosphere. Gas-phase 2,3-dihydroperfluoropentane is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 13-15 years(SRC), calculated from rate constants of 3.01X10-15 to 3.4X10-15 cu cm/molecule-sec(3,4). 2,3-Dihydroperfluoropentane has an estimated 100-year Global Warming Potential of 1500(5) and an atmospheric life-time of 15-23 years(3,5). 2,3-Dihydroperfluoropentane does not contain chromophores that absorb at wavelengths >290 nm(6) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC).

The rate constant for the vapor-phase reaction of 2,3-dihydroperfluoropentane with photochemically-produced hydroxyl radicals has been reported as 3.01X10-15 to 3.4X10-15 cu cm/molecule-sec(1,2). This corresponds to an atmospheric half-life of about 13-15 years at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(3). 2,3-Dihydroperfluoropentane has an estimated 100-year Global Warming Potential of 1500(4) and an atmospheric life-time of 15-23 years(1,4). 2,3-Dihydroperfluoropentane is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(5). 2,3-Dihydroperfluoropentane does not contain chromophores that absorb at wavelengths >290 nm(5) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC).

An estimated BCF of 160 was calculated in fish for 2,3-dihydroperfluoropentane(SRC), using an estimated log Kow of 3.84(1) and a regression-derived equation(1). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is high(SRC), provided the compound is not metabolized by the organism(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc of 2,3-dihydroperfluoropentane can be estimated to be 7800(SRC). According to a classification scheme(2), this estimated Koc value suggests that 2,3-dihydroperfluoropentane is expected to be immobile in soil.

The Henry's Law constant for 2,3-dihydroperfluoropentane is estimated as 0.53 atm-cu m/mole(SRC) derived from its vapor pressure, 225.7 mm Hg(1), and water solubility, 140 mg/L(1). This Henry's Law constant indicates that 2,3-dihydroperfluoropentane is expected to volatilize rapidly from water surfaces(3). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 4.6 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 6.3 days(SRC). However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The estimated volatilization half-life from a model pond is 62 days if adsorption is considered(3). 2,3-Dihydroperfluoropentane's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC).

According to the 2012 TSCA Inventory Update Reporting data, one reporting facility uses 2,3-dihydroperfluoropentane in the United States; the number of workers potentially exposed is unknown due to confidential business information (CBI)(1).|Occupational exposure to 2,3-dihydroperfluoropentane may occur through inhalation and dermal contact with this compound at workplaces where 2,3-dihydroperfluoropentane is produced or used. (SRC)

/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Halogenated aliphatic hydrocarbons and related compounds/|/SRP:/ Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . Cover skin burns with sterile dressings after decontamination ... . /Halogenated aliphatic hydrocarbons and related compounds/|/SRP:/ Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W TKO. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasosupressors if patient is hypotensive with a normal fluid volume. Watch for signs of cardiac irritability and fluid overload ... . Treat seizures with diazepam (Valium) or lorazepam (Ativan) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Halogenated aliphatic hydrocarbons and related compounds/

2H,3H-decafluoropentane

All other chemical product and preparation manufacturing|Pentane, 1,1,1,2,2,3,4,5,5,5-decafluoro-: ACTIVE|PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Gas chromatographic method for determining fluorocarbons in air is described. Concn in air are determined directly. /Fluorocarbons/

Gas chromatography with electron capture analysis of the blood headspace can be used to determine the concentration of halogenated solvents in biological samples. /Halogenated Hydrocarbons-Halogenated Solvents/