2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)benzenesulfonamide
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2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)benzenesulfonamide
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CAS No:
195533-53-0
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Formula:
C13H7F6NO3S
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Chemical Name:
2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)benzenesulfonamide
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Synonyms:
T67; 2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)benzene sulfonamide; 2-fluoro-1-methoxy-4-pentafluorophenyl-sulfonamidobenzene; Batabulin [USAN]; N-(3-fluoro-4-methoxyphenyl)-2,3,4,5,6-pentafluorobenzenesulfonamide; Batabulin; Batabulin (USAN/INN); Batabulin [INN];Expand
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CAS No:
Description
Batabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive, Unresectable, Hepatocellular Carcinoma Patients).|Batabulin is a synthetic pentafluorophenylsulfonamide with potential antineoplastic activity. Batabulin covalently binds to beta tubulin, resulting in a disruption of microtubule polymerization, collapse of the cytoskeleton, cell cycle arrest, and tumor cell apoptosis.
2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)benzenesulfonamide Basic Attributes
371.25500
371.00508323 g/mol
T4NP8G3K6Q
DTXSID70173230
C72716
Computed Properties
Molecular Weight:371.26
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:4
Exact Mass:371.00508323
Monoisotopic Mass:371.00508323
Topological Polar Surface Area:63.8
Heavy Atom Count:24
Complexity:516
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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