Mopidamol
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Mopidamol
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CAS No:
13665-88-8
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Formula:
C19H31N7O4
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Chemical Name:
Mopidamol
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Synonyms:
Ethanol,2,2′,2′′,2′′′-[[4-(1-piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakis-;Ethanol,2,2′,2′′,2′′′-[(4-piperidinopyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetra-;Pyrimido[5,4-d]pyrimidine,ethanol deriv.;2,6-Bis(diethanolamino)-4-piperidinopyrimido[5,4-d]pyrimidine;RA 233;Compound RA-233;Mopidamol
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CAS No:
Description
Mopidamol is a tertiary amino compound and a dialkylarylamine.|Mopidamol is a derivative of dipyridamole that is a phosphodiesterase inhibitor, with potential antiplatelet activity. Mopidamol inhibits the hydrolysis of cyclic nucleotides, such as cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), by cyclic nucleotide phosphodiesterases; thus, cAMP- and cGMP-dependent processes are potentiated. This leads to the induction of prostacyclin synthesis, the inhibition of thromboxane B2 synthesis and prevention of platelet activation and aggregation.|A phosphodiesterase inhibitor which inhibits platelet aggregation. Formerly used as an antineoplastic.
Characteristics
142.20000
-0.94290
1.401g/cm3
157.5 °C
738.6ºC at 760 mmHg
400.5ºC
1.687
6.6E-23mmHg at 25°C
Drug Information
Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)
Mopidamol
Computed Properties
Molecular Weight:421.5
XLogP3:-0.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:11
Exact Mass:421.24375250
Monoisotopic Mass:421.24375250
Topological Polar Surface Area:142
Heavy Atom Count:30
Complexity:474
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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