Distigmine bromide
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Distigmine bromide
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CAS No:
15876-67-2
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Formula:
C22H32N4O4.2Br
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Chemical Name:
Distigmine bromide
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Synonyms:
Pyridinium,3,3′-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-,bromide (1:2);Pyridinium,3-hydroxy-1-methyl-,bromide,hexamethylenebis[methylcarbamate] (2:1);Pyridinium,3,3′-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-,dibromide;3-Hydroxy-1-methylpyridinium bromide,hexamethylenebis[methylcarbamate];BC 51;Distigmine bromide;N,N′-Hexamethylenebis(3-N-methylcarbamoxy-1-methylpyridine)dibromide;Ubretid;Hexamarium;Ubritil;Distigmine dibromide;Hexamarium bromide;Distigmine Br
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CAS No:
Description
Distigmine bromide is an organic bromide salt of distigmine. It is an anticholinesterase drug used for the treatment of myasthenia gravis and postoperative urinary retention. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor. It is a pyridinium salt and an organic bromide salt. It contains a distigmine.
Safety Information
|Danger|H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]|P264, P270, P273, P301+P310, P321, P330, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system. (See all compounds classified as Cholinesterase Inhibitors.)
distigmine
Computed Properties
Molecular Weight:576.3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:576.07698
Monoisotopic Mass:574.07903
Topological Polar Surface Area:66.8
Heavy Atom Count:32
Complexity:487
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
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