Thiosulfuric acid (H2S2O3), lead salt

319 g/mol

319.90554 g/mol

236-780-6|247-566-7

42K67499I7

White crystals

104 Ų

5.18 g/cm³

Decomposes at melting point. (USCG, 1999)|Decomposes

0.03 g/100 cu cm cold water|Soluble in acids and sodium thiosulfate solution

Lead is derived from the decay of radon. /Inorganic lead/|Natural lead is a mixture of four stable isotopes: Pb-204 (1.4%), Pb-206 (25.2%), Pb-207 (21.7%) and Pb-208 (51.7%). Lead isotopes are the end-products of each of the three series of naturally occurring radioactive elements: Pb-206 for the uranium series, Pb-207 for the actinium series and Pb-208 for the thorium series. Forty-three other isotopes of lead, all of which are radioactive, are recognized.|Divalent lead has a strong affinity for inorganic ions containing oxygen (eg, carbonate) or sulfur (sulfide). Lead can also complex with electron rich ligands in many organic cmpd such as amino acids, proteins, and humic acid.

Water soluble.

Sulfite and Thiosulfate Salts

Strong Reducing Agent

Inorganic reducing agents, such as LEAD THIOSULFATE, react with oxidizing agents to generate heat and products that may be flammable, combustible, or otherwise reactive.

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D008, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste. /Lead/

National Toxicology Program. Eleventh Report on Carcinogens (2005). The Report on Carcinogens is an informational scientific and public health document that identifies and discusses substances (including agents, mixtures, or exposure circumstances) that may pose a carcinogenic hazard to human health. Lead and Lead Compounds are listed as reasonably anticipated to be human carcinogens. /Lead and Lead Compounds/[Available from, as of July 31, 2009: http://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s101lead.pdf]

Special Hazards of Combustion Products: Toxic fumes Behavior in Fire: Can emit toxic metal fumes and oxides of sulfur. (USCG, 1999)

|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P261, P264, P270, P271, P273, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P308+P313, P312, P314, P322, P330, P363, P391, P405, and P501|Aggregated GHS information provided by 5 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P261, P264, P270, P271, P281, P301+P312, P304+P312, P304+P340, P308+P313, P312, P314, P330, P405, and P501

Rubber gloves, safety glasses, respirator. (USCG, 1999)|Wear appropriate personal protective clothing to prevent skin contact. /Lead/|Wear appropriate eye protection to prevent eye contact. /Lead/|Respirator Recommendations: Up to 0.5 mg/cu m. /Lead/ [Table#1833]|Respirator Recommendations: Up to 1.25 mg/cu m. /Lead/ [Table#1834]|For more Personal Protective Equipment (PPE) (Complete) data for LEAD THIOSULFATE (9 total), please visit the HSDB record page.

Environmental considerations: Water spill: Neutralize with agricultural lime (CaO) (slaked lime), crushed limestone (CaCO3), or sodium bicarbonate (NaHCO3). Adjust pH to neutral (pH= 7). Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.|Environmental considerations: Land spill: Dig a pit, pond, lagoon, or holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be contained with a flexible impermeable membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.

SRP: Contaminated protective clothing should be segregated in a manner so that results in no direct personal contact by personnel who handle, dispose of, or clean the clothing. Quality assurance procedures to confirm the efficacy of the cleaning procedures should be implemented prior to the decontaminated protective clothing being returned for reuse by the workers. Contaminated clothing (including shoes/socks) should not be taken home at end of shift, but should remain at employee's place of work for cleaning.|SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.|The worker should wash daily at the end of each work shift, and prior to eating, drinking, smoking, etc. /Lead/|Work clothing that becomes wet or significantly contaminated should be removed or replaced. /Lead/|Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises. /Lead/

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Permissible Exposure Limit: The employer shall assure that no employee is exposed to lead at concentrations greater than 50 ug/cu m of air averaged over an 8-hr period. If an employee is exposed to lead for more than 8 hr in any work day, the permissible exposure limit, as a TWA for that day, shall be reduced according to the following formula: Maximum permissible limit (in ug/cu m)=400 divided by the number of hours worked in the day. /Lead, inorganic, as Pb/|The employer shall remove an employee from work having an exposure to lead at or above the action level on each occasion that a periodic and a follow-up blood sampling test conducted pursuant to this section indicate that the employee's blood lead level is at or above 60 ug/100 g of whole blood; and, the employer shall remove an employee from work having an exposure to lead at or above the action level on each occasion that the average of the last three blood sampling tests conducted pursuant to this section (or the average of all blood sampling tests conducted over the previous six (6) months, whichever is longer) indicates that the employee's blood lead level is at or above 50 ug/100 g of whole blood; provided, however, that an employee need not be removed if the last blood sampling test indicates a blood lead level at or below 40 ug/100 g of whole blood. ... The employer shall return an employee to his or her former job status: ... when two consecutive blood sampling tests indicate that the employee's blood lead level is at or below 40 ug/100 g of whole blood. ... The employer shall provide to an employee up to eighteen (18) months of medical removal protection benefits on each occasion that an employee is removed from exposure to lead or otherwise limited pursuant to this section. /Lead, inorganic, as Pb/|Permissible Exposure Limit: The employer shall assure that no employee is exposed to lead at concentrations greater than 50 ug/cu m of air averaged over an 8-hr period. If an employee is exposed to lead for more than 8 hr in any work day, the permissible exposure limit, as a TWA for that day, shall be reduced according to the following formula: Maximum permissible limit (in ug/cu m)=400 divided by the number of hours worked in the day. /Lead, inorganic, as Pb; Shipyard Employment/|The employer shall remove an employee from work having an exposure to lead at or above the action level on each occasion that a periodic and a follow-up blood sampling test conducted pursuant to this section indicate that the employee's blood lead level is at or above 60 ug/100 g of whole blood; and, the employer shall remove an employee from work having an exposure to lead at or above the action level on each occasion that the average of the last three blood sampling tests conducted pursuant to this section (or the average of all blood sampling tests conducted over the previous six (6) months, whichever is longer) indicates that the employee's blood lead level is at or above 50 ug/100 g of whole blood; provided, however, that an employee need not be removed if the last blood sampling test indicates a blood lead level at or below 40 ug/100 g of whole blood. ... The employer shall return an employee to his or her former job status: ... when two consecutive blood sampling tests indicate that the employee's blood lead level is at or below 40 ug/100 g of whole blood. ... The employer shall provide to an employee up to eighteen (18) months of medical removal protection benefits on each occasion that an employee is removed from exposure to lead or otherwise limited pursuant to this section. /Lead, inorganic, as Pb; Shipyard Empolyment/|For more OSHA Standards (Complete) data for LEAD THIOSULFATE (6 total), please visit the HSDB record page.

NIOSH considers "Lead" to mean metallic lead, lead oxides, and lead salts (including organic salts such as lead soaps but excluding lead arsenate).|Recommended Exposure Limit: 10 hr Time-Weighted Avg: 0.050 mg/cu m /Lead/|Air concentrations should be maintained so that worker blood lead remains less than 0.06 mg Pb/100 g of whole blood.

National primary and secondary ambient air quality standards for lead and its compounds, measured as elemental lead by a reference method based on appendix G to this part, or by an equivalent method, are: 1.5 micrograms per cubic meter, maximum arithmetic mean averaged over a calendar quarter. /Lead and its compounds, as Pb/|Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Lead compounds are included on this list. /Lead compounds/

D008; A solid waste containing lead may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste. /Lead/

D008; A solid waste containing lead may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste. /Lead/|The Environmental Protection Agency is ... /promulgated/ regulations concerning ground-water monitoring with regard to screening suspected contamination at land based hazardous waste treatment, storage, and disposal facilities. ... /There are/ new requirements to analyze for a specified core list of chemicals plus those chemicals specified by the Regional Administrator on a site-specific basis. ... /Total lead (all species) is included on this list./ /Total lead (all species)/

Extent of occurrence of /lead/ in earth's crust is about 15 g/ton, also expressed as 0.002% (depth of crust: 16 km). Occurs chiefly as sulfide in galena, other minerals include anglesite (PbSO4), cerussite (PbCO3), mimetite (PbCl2.3Pb3-(AsO4)2) and pyromorphite [PbCl2.3Pb3(PO4)2)].

INHALATION: Joint and muscle pains, headache, dizziness, and insomnia. Weakness, frequently of extensor muscles of hand and wrist (unilateral or bilateral). Heavy contamination - Brain damage. Stupor progressing to coma - with or without convulsion, often death. Excitation, confusion, and mania less common. Cerebrospinal pressure may be increased. INGESTION: Abdominal pain, diarrhea, constipation, loss of appetite, muscular weakness, headache, blue line on gums metalic taste, nausea and vomiting, joint and muscle pain. (USCG, 1999)

Immediately place under medical care. INHALATION: Remove from further exposure. EYES: Flush with copious amounts of water. SKIN: Wash with soap and water. INGESTION: Induce vomiting and follow with gastric lavage at the earliest possible time. Administer a saline cathartic and an enema. (USCG, 1999)

Treatment. Emergency and supportive measures. Treat seizures and coma if they occur. Provide adequate fluids to maintain urine flow but avoid overhydration, which may aggravate cerebral edema. Avoid phenothiazines for delirium , as they may lower the seizure threshold. Patients with increased intracranial pressure may benefit from corticosteroids and mannitol. /Lead/|Specific drugs and antidotes. Treatment with chelating agents decreases blood lead concentrations and increases urinary lead excretion. Although chelation has been associated with improvement in symptoms and decreased mortality, controlled clinical trials demonstrating efficacy are lacking, and treatment recommendations have been largely empiric. Encephalopathy. Administer intravenous calcium EDTA. Some clinicians initiate treatment with a single dose of BAL, followed 4 hours later by concomitant administration of calcium EDTA and BAL. Symptomatic without encephalopathy. Administer oral succimer or parenteral calcium EDTA. Calcium EDTA is preferred as initial treatment if the patient has severe GI toxicity or if the blood lead concentration is extremely elevated. Unithiol may be considered as an alternative to DMSA. Asymptomatic children with elevated blood lead levels. The Centers for Disease Control and Prevention (CDC) recommend treatment of children with levels of 45 mcg/dL or higher. Use oral succimer. A large randomized, double-blind, placebo-controlled trial of DMSA in children with blood lead concentrations between 25 and 44 mcg/dL found no evidence of clinical benefit. Asymptomatic adults. The usual treatment is removal from exposure and observation. Consider oral succimer for patients with markedly elevated levels. Although D-penicillamine is an alternative oral treatment, it may be associated with more side effects and less efficient lead diuresis. Blood lead monitoring during chelation. Obtain a blood lead measurement immediately prior to chelation and recheck the measurement within 24-48 hours after starting chelation to confirm that levels are declining. Recheck measurements 1 and 7 to 21 days after chelation to assess the extent of rebound in blood level associated with redistribution of lead from high bone stores and/or the possibility of reexposure. Additional courses of treatment and further investigation of exposure sources may be warranted. /Lead/|Decontamination. Acute ingestion. Because even small items (eg. a paint chip or a sip of lead-containing glaze) may contain tens to hundreds of milligrams of lead, gut decontamination is indicated after acute ingestion of virtually any lead-containing substance. Administer activated charcoal (although efficacy is unknown). If lead-containing material is still visible on abdominal x-ray after initial treatment, consider whole-bowel irrigation. Consider endoscopic or surgical removal of lead foreign bodies that exhibit prolonged GI retention. Lead-containing buckshot, shrapnel, or bullets in or adjacent to synovial spaces or fluid-filled spaces such as a paravertebral pseudocyst or a subscapular bursa should be surgically removed if possible, particularly if associated with evidence of systematic lead absorption. Enhanced elimination. There is no role for dialysis, hemoperfusion, or repeat-dose charcoal. However, anuric patients with chronic renal failure, limited study suggests that calcium EDTA combined with hemofiltration may increase lead clearance. Other required measures. Remove the patient from the source of exposure and institute control measures to prevent repeated intoxication. Other possibly exposed persons (eg, coworkers or siblings or playmates if young children) should be evaluated promptly. Infants and children. The CDC has recommended universal blood lead screening of children at 12 and 24 months of age in communities where > 27% of dwellings were constructed prior to 1950. For other communities, screening targeted to children from families with low income or other selected risk factors is recommended. General management guidelines are based on the results of the blood lead test: 10-14 mcg/dL: repeat screening; educate parents about risk factors. 15-19 mcg/dL: repeat screening; and if elevated, refer for public health case management to investigate and abate sources. 20-44 mcg/dL: perform complete medical evaluation; refer for case management. 45-69 mcg/dL: perform complete medical evaluation; chelate with oral succimer; refer for case management. 70 mcg/dL or higher: hospitalize child for immediate chelation; refer for case management. Adults with occupational exposure. Federal OSHA standards for workers exposed to lead provide specific guidelines for periodic blood lead monitoring and medical surveillance. Under the general industry standard, workers must be removed from exposure if a single blood lead level exceeds 60 mcg/dL or if the average of three successive levels exceeds 50 mcg/dL. In construction workers, removal is required if a single blood lead level exceeds 50 mcg/dL. Workers may not return to work until the blood lead level is below 40 mcg/dL and any clinical manifestations of toxicity have resolved. Prophylactic chelation is prohibited. OSHA standards mandate that workers removed from work because of elevated blood lead levels retain full pay and benefits. Medical removal parameters in the OSHA standards summarized above were established in the late 1970s and are outdated based on current background blood levels and recent concern about the hazards of lower-level exposure. The standards explicitly empower physicians to order medical removal at lower blood lead levels. It may now be prudent and feasible for employers to maintain workers' blood lead levels below 20 mcg/dL and possibly below 10 mcg/dL. In 2005, the Association of Occupational and Environmental Clinics approved "Medical Management Guidelines for Lead-Exposed Adults" that call for worker protection more stringent than current OSHA standards. /Lead/|Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Lead and related compounds/|For more Antidote and Emergency Treatment (Complete) data for LEAD THIOSULFATE (6 total), please visit the HSDB record page.

Thiosulfuric acid (H2S2O3), lead(2+) salt (1:1): INACTIVE