Muzolimine
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Muzolimine
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CAS No:
55294-15-0
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Formula:
C11H11Cl2N3O
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Chemical Name:
Muzolimine
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Synonyms:
3H-Pyrazol-3-one,5-amino-2-[1-(3,4-dichlorophenyl)ethyl]-2,4-dihydro-;5-Amino-2-[1-(3,4-dichlorophenyl)ethyl]-2,4-dihydro-3H-pyrazol-3-one;BAY-g 2821;Muzolimine;Edrul;3-Amino-1-(1-(3,4-dichlorophenyl)ethyl)-1H-pyrazol-5(4H)-one;37296-93-8
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CAS No:
Description
Muzolimine is a dichlorobenzene.|A pyrazole diuretic with long duration and high capacity of action. It was proposed for kidney failure and hypertension but was withdrawn worldwide because of severe neurological effects.
Drug Information
Agents that promote the excretion of urine through their effects on kidney function. (See all compounds classified as Diuretics.)|Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)
Bay G 2821
Computed Properties
Molecular Weight:272.13
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:271.0279174
Monoisotopic Mass:271.0279174
Topological Polar Surface Area:58.7
Heavy Atom Count:17
Complexity:348
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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