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Home > Encyclopedia > 1-N',4-N'-bis[4-(N'-methylcarbamimidoyl)phenyl]benzene-1,4-dicarboximidamide;tetrahydrochloride

1-N',4-N'-bis[4-(N'-methylcarbamimidoyl)phenyl]benzene-1,4-dicarboximidamide;tetrahydrochloride

1-N',4-N'-bis[4-(N'-methylcarbamimidoyl)phenyl]benzene-1,4-dicarboximidamide;tetrahydrochloride structure

1-N',4-N'-bis[4-(N'-methylcarbamimidoyl)phenyl]benzene-1,4-dicarboximidamide;tetrahydrochloride 

structure
  • CAS No:

    2053-23-8

  • Formula:

    C24H30Cl4N8

  • Chemical Name:

    1-N',4-N'-bis[4-(N'-methylcarbamimidoyl)phenyl]benzene-1,4-dicarboximidamide;tetrahydrochloride

  • Synonyms:

    Amidino TIC;UNII-16MIX5050I;HR 2166;N',N'''-Bis(p-(methylamidino)phenyl)terephthalamidine tetrahydrochloride;2053-23-8;16MIX5050I;Symetamine;NSC57155;NSC 57155;Terephthalamidine, N',N'''-bis(p-(methylamidino)phenyl)-, tetrahydrochloride;Terephthalamidine, N,N''-bis(p-(methylamidino)phenyl)-, tetrahydrochloride;Terephthalamidine, N,N''-bis(p-(N'-methylamidino)phenyl)-, tetrahydrochloride;DTXSID70904763;1,4-Benzenedicarboximidamide, N,N''-bis[4-[imino(methylamino)methyl]phenyl]-, tetrahydrochloride;Q27251829;Terephthalamidine, N,N''-bis(p-(methylamidino)phenyl)- (8CI);N1,N4-bis[4-(N-methylcarbamimidoyl)phenyl]benzene-1,4-dicarboxamidine;N1,N4-bis[4-(N-Methylcarbamimidoyl)phenyl]benzene-1,4-dicarboximidamide;1,4-Benzenedicarboximidamide, N,N''-bis(4-(imino(methylamino)methyl)phenyl)-, tetrahydrochloride (9CI)

Description

Amidino TIC is one of 800 terephthalanilides synthesized and tested preclinically in the late 1950's and early 1960's. Chosen in the 1990's for further clinical investigation by the NCI's Project for the Review of Old Drugs because of its structure and activity spectrum.

1-N',4-N'-bis[4-(N'-methylcarbamimidoyl)phenyl]benzene-1,4-dicarboximidamide;tetrahydrochloride Basic Attributes

572.4 g/mol

572.131804 g/mol

16MIX5050I

C45690

Characteristics

154 Ų

Computed Properties

Molecular Weight:572.4
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:572.131804
Monoisotopic Mass:570.134754
Topological Polar Surface Area:154
Heavy Atom Count:36
Complexity:654
Covalently-Bonded Unit Count:5
Compound Is Canonicalized:Yes

Guide of 1-N',4-N'-bis[4-(N'-methylcarbamimidoyl)phenyl]benzene-1,4-dicarboximidamide;tetrahydrochloride

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