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2-Aminobenzimidazole

2-Aminobenzimidazole structure

2-Aminobenzimidazole 

structure
  • CAS No:

    934-32-7

  • Formula:

    C7H7N3

  • Chemical Name:

    2-Aminobenzimidazole

  • Synonyms:

    1H-Benzimidazol-2-amine;Benzimidazole,2-amino-;2-Aminobenzimidazole;2-Iminobenzimidazoline;2-Benzimidazolamine;2-AB;2-Amino-1H-benzimidazole;2-Benzimidazolylamine;1H-Benzimidazol-2-ylamine;NSC 27793;NSC 7628;A 0850;2-Aminobenzoimidazole;1H-1,3-Benzodiazol-2-amine;1H-Benzoimidazol-2-ylamine;144704-99-4

  • Categories:

    Analytical Chemistry  >  Standard

Description

light yellow to cream or beige powder or flakes


Plates (in water); white powder. (NTP, 1992)


Plates (in water); white powder. (NTP, 1992)|2-aminobenzimidazole is a member of the class of benzimidazoles that is benzimidazole in which the hydrogen at position 2 is replaced by an amino group. It has a role as a marine xenobiotic metabolite.

2-Aminobenzimidazole Basic Attributes

133.15

133.15

116525

213-280-6

E65DE7521V

27793|7628

DTXSID1024465

29339990

Characteristics

54.7

0.9

Yellow to beige or light brown Crystalline Powder, Crystals or Flakes

1.4±0.1 g/cm3

229-231 °C

368.9ºC at 760 mmHg

204.6±10.4 °C

1.780

soluble in water (Slightly).

Store below +30°C.

Oral-mouse LD40: 600 mg/kg; Oral-rat LD50: 500 mg/kg

Flammable; burning produces toxic nitrogen oxide fumes

Insoluble in water.

Amines, Phosphines, and Pyridines

2-AMINOBENZIMIDAZOLE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Safety Information

NONH for all modes of transport

3

22-36/37/38-43

26-36/37/39-22

DD5775000

Xn

Warehouse ventilated, low temperature and dry

Stable under normal temperatures and pressures.

P261-P280-P305 + P351 + P338

H302-H315-H317-H319-H335

Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P272, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 105 companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material under ambient temperatures. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Toxicity

moderately toxic

Drug Information

ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of nitrogen oxides. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

2-aminobenzimidazole

2-Aminobenzimidazole Use and Manufacturing

Uses

2-Aminobenzimidazole was used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles

1H-Benzimidazol-2-amine: ACTIVE

Transformation products|Pesticides -> Fungicides -> Benzimidazole fungicides -> Transformation products|Environmental transformation -> Pesticide transformation products (metabolite, successor)

2-Aminobenzimidazole is a known environmental transformation product of Carbendazim.|2-AB is a known environmental transformation product of Thiophanate-methyl.

Computed Properties

Molecular Weight:133.15
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Exact Mass:133.063997236
Monoisotopic Mass:133.063997236
Topological Polar Surface Area:54.7
Heavy Atom Count:10
Complexity:126
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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