1H-INDOLE,5-BROMO-2-PHENYL-

In a nitrogen-protected atmosphere, add 0.2 mmol of 2-phenyl-5-bromo-indole to a 25 mL reaction tube containing a polytetrafluoroethylene magnetic stirrer.0.24 mmol of trifluoroacetylhydrazine, 0.7 mmol of potassium tert-butoxide, 0.3 mmol of di-tert-butyl peroxide (DTBP), 0.05 mmol Cu2S, 0.2mmol of magnesium trifluoromethanesulfonate was finally added with 1-2mL of solvent 1, 2-dichloroethane, and the reaction was stirred in a closed system at 120 C for 12 hours and then cooled to room temperature.The reaction mixture was diluted with ethyl acetate, washed with saturated NaHCO3 solution and saturated brine, and the organic phase was dried over anhydrous MgSO4, filtered and the solvent was removed by rotary evaporation, using n-pentane and ethyl acetate as eluents.3, 3 '-(2, 2, 2-trifluoroethyl) bis (In a nitrogen-protected atmosphere, add 0.2 mmol of 2-phenyl-5-bromo-indole to a 25 mL reaction tube containing a polytetrafluoroethylene magnetic stirrer.0.24 mmol of trifluoroacetylhydrazine, 0.7 mmol of potassium tert-butoxide, 0.3 mmol of di-tert-butyl peroxide (DTBP), 0.05 mmol Cu2S, 0.2mmol of magnesium trifluoromethanesulfonate was finally added with 1-2mL of solvent 1, 2-dichloroethane, and the reaction was stirred in a closed system at 120 C for 12 hours and then cooled to room temperature.The reaction mixture was diluted with ethyl acetate, washed with saturated NaHCO3 solution and saturated brine, and the organic phase was dried over anhydrous MgSO4, filtered and the solvent was removed by rotary evaporation, using n-pentane and ethyl acetate as eluents.3, 3 '-(2, 2, 2-trifluoroethyl) bis (

Molecular Weight:272.14
XLogP3:4.4
Hydrogen Bond Donor Count:1
Rotatable Bond Count:1
Exact Mass:270.99966
Monoisotopic Mass:270.99966
Topological Polar Surface Area:15.8
Heavy Atom Count:16
Complexity:237
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes