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5-Hydroxyeicosapentaenoic acid

5-Hydroxyeicosapentaenoic acid structure

5-Hydroxyeicosapentaenoic acid 

structure
  • CAS No:

    92008-51-0

  • Formula:

    C20H30O3

  • Chemical Name:

    5-Hydroxyeicosapentaenoic acid

  • Synonyms:

    6,8,11,14,17-Eicosapentaenoic acid,5-hydroxy-,(5S,6E,8Z,11Z,14Z,17Z)-;6,8,11,14,17-Eicosapentaenoic acid,5-hydroxy-,[S-(E,Z,Z,Z,Z)]-;(5S,6E,8Z,11Z,14Z,17Z)-5-Hydroxy-6,8,11,14,17-eicosapentaenoic acid;5-HEPE;5-Hydroxyeicosapentaenoic acid

5-Hydroxyeicosapentaenoic acid Basic Attributes

318.450

318.45

DTXSID10390601

Characteristics

57.53000

4.88

1.0±0.1 g/cm3

488.0±45.0 °C at 760 mmHg

263.1±25.2 °C

1.526

5-Hydroxyeicosapentaenoic acid Use and Manufacturing

5(S)-HEPE is produced by 5-lipoxygenase catalyzed oxidation of eicosapentaenoic acid (EPA). While the synthesis of 5(S)-HEPE from EPA by tissue homogenates has been demonstrated, the biological activity of 5(S)-HEPE is poorly documented. It remains to be determined whether this activity differs substantially from that of 5(S)-HETE .

Computed Properties

Molecular Weight:318.4
XLogP3:4.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:13
Exact Mass:318.21949481
Monoisotopic Mass:318.21949481
Topological Polar Surface Area:57.5
Heavy Atom Count:23
Complexity:428
Undefined Atom Stereocenter Count:1
Undefined Bond Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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