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Deoxycorticosterone

Deoxycorticosterone structure

CAS No:
64-85-7
Formula:
C21H30O3
Chemical Name:
Deoxycorticosterone
Synonyms:
Pregn-4-ene-3,20-dione,21-hydroxy-;11-Deoxycorticosterone;21-Hydroxypregn-4-ene-3,20-dione;Cortexone;11-Dehydroxycorticosterone;Deoxycortone;Desoxycorticosterone;11-Desoxycorticosterone;Desoxycortone;DOC;21-Hydroxy-Δ4-pregnene-3,20-dione;21-Hydroxyprogesterone;Kendall's desoxy compound B;4-Pregnen-21-ol-3,20-dione;Reichstein's substance Q;Corticosterone,11-deoxy-;Deoxycorticosterone;Δ4-Pregnene-21-ol-3,20-dione;21-Hydroxy-3,20-dioxopregn-4-ene;21-Hydroxy-Δ4-pregnane-3,20-dione;DOC (steroid);NSC 11319;30598-81-3
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor.

11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone (BAN), and cortexone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone. It is an active (Na+-retaining) mineralocorticoid. As its names indicate, 11-deoxycorticosterone can be understood as the 21-hydroxy- variant of progesterone or as the 11-deoxy- variant of corticosterone.

Deoxycorticosterone Basic Attributes

Molecular Weight：

330.46

Exact Mass：

330.46

EC Number：

200-596-4

NSC Number：

11319

HScode：

2942000000

Characteristics

PSA：

54.4

XLogP3：

2.88

Appearance：

Solid

Density：

1.22 g/cm³

Melting Point：

141.5 °C

Boiling Point：

488ºC at 760 mmHg

Flash Point：

9℃

Refractive Index：

1.559

Water Solubility：

H2O: slightly soluble

Storage Conditions：

-20°C

Specific rotation：

184 º (c=1, C2H5OH)

Collision Cross Section：

186.5 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|184.42 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]

Safety Information

Transport codes：

UN 2811 6.1/PG 2

wgk germany：

hazard class code：

40-48-39/23/24/25-23/24/25-11

safety instructions：

22-24/25-45-36/37-16-7

RTECS Number：

HG0350000

Marks：

Xn,T,F

Stability/Shelf Life：

Stable under normal temperatures and pressures.

Precautionary statement(s)：

P210-P260-P280-P301 + P310-P311

Hazard Statements：

H225-H301 + H311 + H331-H370

RIDADR：

UN 2811

Deoxycorticosterone Use and Manufacturing

Antiinflammatory;Corticoide

Computed Properties

Molecular Weight:330.5
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:330.21949481
Monoisotopic Mass:330.21949481
Topological Polar Surface Area:54.4
Heavy Atom Count:24
Complexity:606
Undefined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Synthesis Route

6251-69-0

3885-55-0

10385-97-4

3885-55-0

Recommended Suppliers of Deoxycorticosterone

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High purity Desoxycorticosterone 99% high quality see COA KANBEI

CAS No.: 64-85-7

Grade: Industrial Grade

Content: 99%

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