1,1′-Sulfonylbis[4-bromobenzene]
-
![1,1′-Sulfonylbis[4-bromobenzene] structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/125626db767143e19d264744bbf85cf0.png "1,1′-Sulfonylbis[4-bromobenzene]")
1,1′-Sulfonylbis[4-bromobenzene]
structure -
-
CAS No:
2050-48-8
-
Formula:
C12H8Br2O2S
-
Chemical Name:
1,1′-Sulfonylbis[4-bromobenzene]
-
Synonyms:
Benzene,1,1′-sulfonylbis[4-bromo-;Sulfone,bis(p-bromophenyl);1,1′-Sulfonylbis[4-bromobenzene];Bis(p-bromophenyl) sulfone;4,4′-Dibromodiphenyl sulfone;Bis(4-bromophenyl) sulfone;NSC 43047;Di(4-bromophenyl) sulfone;1-Bromo-4-(4-bromophenyl)sulfonylbenzene
- Categories:
-
CAS No:
Safety Information
|Warning|H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P280, P305+P351+P338, and P337+P313|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory.
1,1′-Sulfonylbis[4-bromobenzene] Use and Manufacturing
4-Bromobenzenesulfonyl chloride (5.00 g, 19.69 mmol) and bromobenzene (4.61 g, 29.54 mmol) were added to a 250 mL three-necked flask.Dissolve in 40 mL of dichloromethane and add ferric chloride (6.34 g, After 39.39 mmol), the reaction solution was heated to 40 ° C and stirred for 6 h.The reaction solution was cooled to room temperature, and 30 mL of dichloromethane was slowly added thereto.50 mL of 1 M dilute hydrochloric acid and stirring for 10 min, the mixed solution was poured into a separatory funnel, the organic layer solution was taken, and the aqueous layer was extracted three times with dichloromethane.The organic layers were combined, dried over anhydrous sodium sulfate and filtered.The resulting filtrate was spin-dried using a rotary evaporator.The crude product was purified by silica gel column chromatography using a mixture of n-hexane and dichloromethane in a volume ratio of 4:5. The product was dried in vacuo to give a white powder.6.48 g, yield 88percent.To a solution of 30mL HWell dried 250 mL three-necked round bottom flask charged with bis (4-bromophenyl) sulfane (9 g, 26.2 mmol), 30percent hydrogenperoxide 50 mL and acetic acid 100 mL was stirred at 100°C for 10 hours. After completion of the reaction, it was extracted three times using methylenechloride (MC). The extracted organic layer was dried to remove water using MgSO4 and the solvent was removed using a rotary evaporator, separated by column chromatography using MC to obtain compound 5 g (yield = 51percent).General procedure: A mixture of the sodium arylsulfinate (1 mmol), Cu(OAc)2 (0.5 mmol)and CH3CN (1 mL) was stirred at 60 °C in air for 3 h. After this, themixture was cooled to room temperature and filtered through a filterpaper. The organic phases were evaporated under reduced pressure andthe residue was subjected to flash column chromatography (silica gel, ethyl acetate/petroleum ether = 1/10) to obtain the desired product.All products are known compounds and were characterised by 1HNMR, 13C NMR and HRMS.
Computed Properties
Molecular Weight:376.07
XLogP3:4.2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:375.85913
Monoisotopic Mass:373.86118
Topological Polar Surface Area:42.5
Heavy Atom Count:17
Complexity:306
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 1,1′-Sulfonylbis[4-bromobenzene]
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of fine chemicals,pharmaceutical materials -
![China]()
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 2050-48-8Grade: Industrial GradeContent: 99% -
![China]()
CN
4 YRS
Business licensedTrader Supplier of API OLED Organic intermediate -
![China]()
CN
2 YRS
Business licensed Certified factoryManufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acidInquiryCAS No.: 2050-48-8Grade: Industrial GradeContent: 95%
Learn More Other Chemicals
-
2-Bromophenacyl bromide, 90%
49851-55-0
-
1H-Indazol-7-ol
81382-46-9
-
6-Chloro-4-forMyl-nicotinic acid
1031433-06-3
-
3-Hydroxy-2,4,5-trifluorobenzoic acid Formula
116751-24-7
-
2-Methyl-1-heptene Formula
15870-10-7
-
1-(3,5-Dinitrophenyl)ethanone Formula
14401-75-3
-
α-Amino-3-bromobenzeneacetic acid Structure
79422-73-4
-
6-(BROMOMETHYL)-1,3-BENZOTHIAZOLE,97% Structure
499770-85-3
-
What is Allyl methacrylate
96-05-9
-
What is ethyl 5-hydroxy-2-Methylnicotinate
60390-47-8
1,1′-Sulfonylbis[4-bromobenzene]
SDSRequest for Quotation