(±)-Desethylhydroxychloroquine
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(±)-Desethylhydroxychloroquine
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CAS No:
4298-15-1
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Formula:
C16H22ClN3O
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Chemical Name:
(±)-Desethylhydroxychloroquine
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Synonyms:
Ethanol,2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]amino]-;Ethanol,2-[[4-[(7-chloro-4-quinolyl)amino]pentyl]amino]-;2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]amino]ethanol;Cletoquine;(±)-Desethylhydroxychloroquine;Desethylhydroxychloroquine;137360-11-3
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CAS No:
Description
Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment[1][2].
Computed Properties
Molecular Weight:307.82
XLogP3:2.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:307.1451400
Monoisotopic Mass:307.1451400
Topological Polar Surface Area:57.2
Heavy Atom Count:21
Complexity:293
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes