Copper phthalocyanine

576.07

575.079390 g/mol

4121848

205-685-1

1638

DTXSID8027117

Bright blue microcrystals with purple lustre|Dark blue powder|A bright blue copper phthalocyanine pigment.|Purple needles and/or powder /sublimed grade, dye content 99%/

32041300

84.02000

1.46190

Dark blue Fine Crystalline Powder

1.62 g/cm³

480 °C

<0.1 g/100 mL at 20 ºC

Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.

3.17X10-19 mm Hg at 25 °C (est)

Oral-Rat LD:> 15000 mg/kg; peritoneal-rat LD:> 3000 mg/kg

Flammable, the fire emits spicy and irritating smoke containing copper and nitrogen oxides

Decomposed by hot nitric acid, or dilute acid permanganate to yield phthalimide|Crystalline and analytically pure sublimate obtained at about 580 °C in low pressure atmosphere of nitrogen or carbon dioxide; stable toward heat, alkalies, dilute acids|In aqueous solutions of strong oxidants, the phthalocyanine ring is completely destroyed and oxidized to phthalimide.|Displays an overall good-to-excellent fastness in all categories.

> 350 °C

-

R36/37/38; R48; R41; R37/38; R20/21/22

22-24/25

GL8510000

Xi; Xn

Warehouse low temperature, ventilated, dry

Stable under normal temperatures and pressures.

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.

Materials to avoid: strong oxidizing agents

The color additive [phthalocyaninato(2-)] copper may be safely used to color polypropylene sutures, polybutester (the generic designation for the suture fabricated from 1,4-benzenedicarboxylic acid, polymer with 1,4-butanediol and alpha -hydro- omega - hydroxypoly(oxy-1,4-butanediyl), CAS Reg. No. 37282-12-5) nonabsorbable sutures for use in general and ophthalmic surgery, polybutylene terephthalate nonabsorbable monofilament sutures for general and ophthalmic surgery, nonabsorbable sutures made from poly(vinylidene fluoride) and poly(vinylidene fluoride-co-hexafluoropropylene) for general and ophthalmic surgery, and polymethylmethacrylate monofilament used as supporting haptics for intraocular lenses, subject to the following restrictions: (i) The quantity of the color additive does not exceed 0.5 percent by weight of the suture or haptic material. (ii) The dyed suture shall conform in all respects to the requirements of the U.S. Pharmacopeia. (2) The color additive [phthalocyaninato(2-)] copper may be safely used for coloring contact lenses in amounts not to exceed the minimum reasonably required to accomplish the intended coloring effect.

European Commission, ESIS; IUCLID Dataset, Tetrabenzo-5,10,15,20-diazaporphyrinephthalocyanine (147-14-8) (2000 CD-ROM edition) contains information on use, toxicology, and environmental effects of this chemical as supplied to the European Union by industry.[Available from, as of April 27, 2010: http://esis.jrc.ec.europa.eu/]|Organization for Economic Cooperation and Development; Screening Information Data Set for Copper phthalocyanine, CAS #147-14-8 p.143 (1993). This OECD Initial Assessment of HPV Chemicals is part of a series of OECD SIDS documents published by UNEP Chemicals to facilitate the access to information needed for health and environmental risk assessments of chemicals.[Available from, as of April 27, 2010: http://www.chem.unep.ch/irptc/sids/OECDSIDS/sidspub.html]

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

Protective gloves. Safety goggles|Personal protection: P1 filter respirator for inert particles.

Difficult to ignite /From German/

Not explosive

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self contained breathing apparatus for fire fighting if necessary.

Sweep spilled substance into containers. Carefully collect remainder, then remove to safe place.

SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

May cause eye irritation. May cause skin irritation. May cause respiratory tract irritation.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached.

Avoid inhalation of dust.

Protective gloves.

Wear safety goggles.

| 0 - Materials that, under emergency conditions, would offer no hazard beyond that of ordinary combustible materials.| 0 - Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand.| 0 - Materials that in themselves are normally stable, even under fire conditions.

Heavy-metal residues in effluents from dye production pose a risk of water pollution(1). /Metal complex dyes/

nontoxic

LD50 Rat oral > 10,000 mg/kg bw|LD50 Rabbit oral 16,000 mg/kg bw

Pigment Blue's production and use as a pigment in inks and paints, in polypropylene sutures(1), alkyd resin enamels, lacquers, rubber, resins, papers, tinplate printing, colored chalks and pencils(2), linoleum, leather cloth, wall paper, artists' materials, wax compositions and cements, textile printing, mass pigmentation of viscose(3), synthesis of Direct Blue 86, Pigment Green 36, Reactive Blue 7, and Vat Blue 29(4), and in dyestuffs such as direct and reactive dyes, water-soluble dyes, solvent-soluble dyes, azo-reactive dyes, azo non-reactive dyes, sulfur dyes, and vat dyes(5) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Pigment Blue 15 is an insoluble chelate(1) that binds to surfaces, particularly to clay, by ion-exchange processes(2), and absorbs to mineral surfaces such as goethite(3). Therefore, Pigment Blue 15 is expected to absorb to soils(SRC). Volatilization from moist soil surfaces is not expected to be an important fate process as this compound is a chelate, which tend to be stabile in the environment(2,4). Pigment Blue 15 is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 3.2X10-19 mm Hg at 25 °C(SRC), determined from a fragment constant method(5). A 0% of theoretical BOD using activated sludge in the Japanese MITI test(6) suggests that biodegradation of Pigment Blue 15 in the environment may be limited(SRC).|AQUATIC FATE: Pigment Blue 15 is an insoluble chelate(1) that binds to surfaces, particularly to clay, by ion-exchange processes(2), and absorbs to mineral surfaces such as goethite(3). Therefore, Pigment Blue 15 is expected to absorb to aquatic soils and sediments(SRC). It is not expected to undergo volatilization(2) as this compound is a chelate, which tend to be stabile in the environment(4). According to a classification scheme(5), experimental BCF values of less than 0.33 to 11 (test concentration = 0.6 mg/L) and less than 3.6 (test concentration = 0.06 mg/L)(6), suggest the potential for bioconcentration in aquatic organisms is low(SRC). A 0% of theoretical BOD using activated sludge in the Japanese MITI test(6) suggests that biodegradation of Pigment Blue 15 in the environment may be limited(SRC).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), Pigment Blue 15, which has an estimated vapor pressure of 3.2X10-19 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase Pigment Blue 15 may be removed from the air by wet or dry deposition(SRC). Pigment Blue 15 absorbs light at 678 nm(3) and therefore may be susceptible to direct photolysis by sunlight(SRC).

Pigment Blue 15 is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(1). Pigment Blue 15 absorbs light at 678 nm(2) and therefore may be susceptible to direct photolysis by sunlight(SRC). Pigment Blue 15 is a copper chelate(SRC). Chelating agents are essentially environmentally benign under the conditions of incidental to normal handling and use(3). Chelate stability is related to the formation of strain-free five-and six-membered rings, to the number of chelate rings per ligand, to the basicity of the ligands, and to the nature of the metal ion. Chelation leads to changes in many physical and chemical properties, including absorption spectra, stability, charge and solubility(4).

Experimental BCF values, measured over 6 weeks in carp, for Pigment Blue 15 range from less than 0.33 to 11 at a test concentration of 0.6 mg/L and less than 3.6 at a test concentration of 0.06 mg/L(1). According to a classification scheme(2), these BCF values suggest the potential for bioconcentration in aquatic organisms is low(SRC). Studies indicate that the dyes are not bioaccumulated because solubilities in water are either too high or too low(3).

Pigment Blue 15 is an insoluble copper chelate(1) that binds to surfaces, particularly to clay, by ion-exchange processes(2), and absorbs to mineral surfaces such as goethite(3). Therefore, Pigment Blue 15 is expected to be immobile in soils(SRC). It has been observed using biodegradation studies that between 40 and 80% of the material is adsorbed to activated sludge(4).

Pigment Blue 15 is a copper chelate(SRC). Volatilization from moist soil surfaces is not expected to be an important fate process as chelates tend to be stable in the environment(1,2). Chelate stability is related to the formation of strain-free five-and six-membered rings, to the number of chelate rings per ligand, to the basicity of the ligands, and to the nature of the metal ion(3,4). Pigment Blue 15 is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 3.2X10-19 mm Hg at 25 °C(SRC), determined from a fragment constant method(5).

According to the 2006 TSCA Inventory Update Report, the number of perons reasonably likely to be exposed in the industrial manufacturing, processing, and use of Pigment Blue 15 is 1000 or greater; the data may be greatly underestimated(1).|NIOSH (NOES Survey 1981-1983) has statistically estimated that 104,851 workers (25,691 of these were female) were potentially exposed to Pigment Blue 15 in the US(1). Occupational exposure to Pigment Blue 15 may occur through inhalation of dust and dermal contact with this compound at workplaces where Pigment Blue 15 is produced or used. Use data indicate that the general population may be exposed to Pigment Blue 15 via dermal contact with the compound or other consumer product containing Pigment Blue 15(SRC).

Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS. (See all compounds classified as Coloring Agents.)|Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant and Hackh's Chemical Dictionary, 5th ed, p301, p499) (See all compounds classified as Indicators and Reagents.)

Fresh air, rest.

Remove contaminated clothes.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/|/SRP:/ Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poisons A and B/|/SRP:/ Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poisons A and B/

copper phthalocyanine

Dry color, presscake and aqueous dispersions; flushed pigment grade|Stabilized forms /of Pigment Blue 15/ exist as the noncrystallizing (NC) types, eg, Pigment Blue 15:1, and the noncrystallizing, nonflocculating (NCNF) types eg, Pigment Blue 15:2|Available in alpha or beta crystal modification.

All other chemical product and preparation manufacturing|Copper, [29H,31H-phthalocyaninato(2-)-.kappa.N29,.kappa.N30,.kappa.N31,.kappa.N32]-, (SP-4-1)-: ACTIVE|Exists in 2 forms: thermodynamically less stable, redder alpha-form is better pigment than more stable greener beta-form. In presence of aromatic solvents, heat, high shear, etc, alpha-form is converted to beta-form.|The alpha form is usually obtained by conversion from the beta form and has to be stabilized to prevent phase reconversion.|Heating o-dichlorobenzene with quinoline, copper (I) bromide, and copper (I) cyanide at 205 to 220 °C for 4.5 hrs gives crude, well-crystallized [pigment blue 15] (71% yield).|/Pigment blue 15/ can ... be made by milling of diiminoisoindolenine, copper (I) chloride, anhydrous sodium sulfate, of ethylene glycol for 3 hours at 100 to 110 °C... the product is suitable as a pigment. Other solvents and additives are also used for the reaction.|For more General Manufacturing Information (Complete) data for Pigment Blue 15 (7 total), please visit the HSDB record page.

EPA Safer Chemical Functional Use Classes -> Colorants|Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern|Cosmetics -> Hair dyeing