Fluproquazone
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Fluproquazone
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CAS No:
40507-23-1
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Formula:
C18H17FN2O
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Chemical Name:
Fluproquazone
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Synonyms:
2(1H)-Quinazolinone,4-(4-fluorophenyl)-7-methyl-1-(1-methylethyl)-;4-(4-Fluorophenyl)-7-methyl-1-(1-methylethyl)-2(1H)-quinazolinone;1-Isopropyl-4-(4-fluorophenyl)-7-methyl-2(1H)-quinazolinone;RF 46-790;Fluproquazone;Tormosyl;SaH 46-790;1-Isopropyl-7-methyl-4-(p-fluorophenyl)-quinazolin-2(1H)-one;100926-69-0
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CAS No:
Characteristics
32.7
4.09190
1.18g/cm3
172-174 °C
436.6ºC at 760 mmHg
217.9ºC
1.596
LD50 in mice, rats, rabbits (mg/kg): >5000, >3000, 742 orally (Rüttimann)
Drug Information
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
4-(p-fluorophenyl)-1-isopropyl-7-methyl-quinazolin-2(1H)-one