 Home > Encyclopedia > tert-Butoxycarbonyl-L-isoleucine

tert-Butoxycarbonyl-L-isoleucine

tert-Butoxycarbonyl-L-isoleucine structure

CAS No:
13139-16-7
Formula:
C11H21NO4
Chemical Name:
tert-Butoxycarbonyl-L-isoleucine
Synonyms:
L-Isoleucine,N-[(1,1-dimethylethoxy)carbonyl]-;Isoleucine,N-carboxy-,N-tert-butyl ester,L-;N-[(1,1-Dimethylethoxy)carbonyl]-L-isoleucine;tert-Butoxycarbonyl-L-isoleucine;N-(tert-Butoxycarbonyl)-L-isoleucine;N-(tert-Butyloxycarbonyl)-L-isoleucine;N-Carboxyisoleucine N-tert-butyl ester;N-tert-Butoxycarbonylisoleucine;BOC-isoleucine;BOC-L-isoleucine;NSC 334311;N-t-Boc-L-isoleucine;(2S,3S)-2-[(tert-Butoxycarbonyl)amino]-3-methylpentanoic acid;N-Boc-L-isoleucine;(2S,3S)-2-(tert-Butoxycarbonylamino)-3-methylpentanoic acid;251308-24-4;444189-87-1;760894-13-1;1055073-60-3;1133711-09-7;1161436-41-4;1236362-46-1;1324010-81-2;1357914-00-1;1396967-46-6;1447604-29-6;1567347-11-8;2242531-25-3;2375242-18-3
Categories:
Biochemical Engineering > Amino Acids and Derivatives

Request for Quotation

tert-Butoxycarbonyl-L-isoleucine Basic Attributes

Molecular Weight：

231.29

Exact Mass：

231.29

BRN：

1711700

EC Number：

236-074-8

HScode：

2924199090

Characteristics

PSA：

75.6

XLogP3：

1.6

Appearance：

white powder and chunks

Density：

1.1±0.1 g/cm3

Melting Point：

48-52 °C

Boiling Point：

356°C at 760 mmHg

Flash Point：

169.1±23.2 °C

Refractive Index：

1.461

Water Solubility：

soluble in methanol. Insoluble in water.

Storage Conditions：

−20°C

Vapor Pressure：

0mmHg at 25°C

Specific rotation：

2 º (c=2,CH3COOH)

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

20/21/22-36/37/38

safety instructions：

24/25-36-26

Marks：

Stability/Shelf Life：

Stable at room temperature in closed containers under normal storage and handling conditions.

Precautionary statement(s)：

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H315

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

tert-Butoxycarbonyl-L-isoleucine Use and Manufacturing

Methods of Manufacturing

A solution of L-Isoleucine (1.31 g, 10 mmol, 1.0 equiv.) in 20.5 mL 1M NaOH was cooled in an ice-bath and Boc3.00 mg (22.87 mmol) of L-isoleucine (S)-11 is introduced in a 300 ml egg plant type flask and dissolved by adding 21 ml of 1N-NaOH, Furthermore, 15 ml of water, 15 ml of dioxane and 5.49 mg (25.15 mmol) of Boc2O are added and stirred at room temperature for 5 hours, and additional 2.70 mg (12.37 mmol) of Boc2O are added and stirred at room temperature for 13 hours. The reaction solution is washed for three times with 30 ml of ether, pH is adjusted to 2-3 by adding citric acid to an aqueous layer in an ice bath, and thereafter it is washed twice with 50 ml of diethyl ether, extracted twice with 30 ml of ethyl acetate, washed for 5 times with 20 ml of water, dried with sodium sulfate and distilled off the solvent, to obtain 4.69 g (yield; 88.7percent) of a Boc form (S)-12 of L-isoleucine as colorless oil.General procedure: l-lysine, l-alanine, l-leucine, l-isoleucine, l-phenylalanine, l-threonine (5g, 1 equiv) was dissolved in H

Uses

Used in biochemical reagents and peptide synthesis.

Manufacturing Info：

L-Isoleucine, N-[(1,1-dimethylethoxy)carbonyl]-: INACTIVE

Computed Properties

Molecular Weight:231.29
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:231.14705815
Monoisotopic Mass:231.14705815
Topological Polar Surface Area:75.6
Heavy Atom Count:16
Complexity:257
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Hexane

Sodium hydroxide

Ethyl acetate

Acetic acid

tert-Butanol

Recommended Suppliers of tert-Butoxycarbonyl-L-isoleucine

LEADER BIOCHEMICAL GROUP Contact Supplier

CN
8 YRS

Business licensed Certified factory

Manufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances Chemicals

China Largest factory Manufacturer Supply High Qulity BOC-L-ISOLEUCINE CAS 13139-16-7

CAS No.: 13139-16-7

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Boc-L-Isoleucine

CAS No.: 13139-16-7

Content: 99.00%

Inquiry

Learn More Other Chemicals

L-Cysteine

52-90-4
1-chloro-6-Methyl-5-nitroisoquinoline

943606-84-6
2-chloro-N-(2-oxothiolan-3-yl)acetamide

84611-22-3
N-[(Phenylmethoxy)carbonyl]-L-phenylalanylglycine Formula

13122-99-1
(αR)-α-[(Methoxycarbonyl)amino]benzeneacetic acid Formula

50890-96-5
3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide Formula

461000-66-8
5-(4-Hydroxyphenyl)-2,4-imidazolidinedione Structure

2420-17-9
γ-Aminobenzenepropanol Structure

14593-04-5
What is tert-Butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate

170491-63-1
What is (R)-3-AMINO-3-(4-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID

774178-39-1

Hot Searches: phenacetin drug; poly methyl acrylate; zinc carbonate; potassium sulfide formula; dichlorine monoxide; barium sulfate formula

Guide of tert-Butoxycarbonyl-L-isoleucine

Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Material
Recommended Suppliers
Learn More Other Chemicals

tert-Butoxycarbonyl-L-isoleucine

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.