Product
Supplier
Encyclopedia
Inquiry
Home > Active Pharmaceutical Ingredients
In the chemical industry, API is Active Pharmaceutical Ingredients, meaning the active ingredients in pharmaceutical products. It is the core substance for producing the intended therapeutic effect. The quality of Active Pharmaceutical Ingredients is critical to the safety and efficacy of the final pharmaceutical product. Therefore, the production of API chemicals involves strict regulatory guidelines and standards, such as GMP (Good Manufacturing Practices) and GLP (Good Laboratory Practices). On ECHEMI, you can select API chemical products on your demand from various active pharmaceutical ingredient manufacturers and distributors.

Active Pharmaceutical Ingredients Suppliers

Buying Active Pharmaceutical Ingredients (APIs) can still be challenging, especially when quality, compliance, and supply stability matter most. On ECHEMI, you can access 742 qualified manufacturers and 377 verified distributors across China, India, the USA, Europe, and other regions. Compare API specifications, review compliance standards, and connect directly with reliable suppliers to support your pharmaceutical production and research needs.
Explore active pharmaceutical ingredients for your specific needs now.
4830 Active Pharmaceutical Ingredients items

Desloratadine

CAS No: 100643-71-8

Formula: C19H19ClN2

Categories: Active Pharmaceutical Ingredients > Antiallergic Drugs

Beige SolidChEBI: Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness.Desloratadine is a second generation of tricyclic antihistamine. It is a H1-receptor antagonist which has anti-inflammaMore

Flurbiprofen

CAS No: 5104-49-4

Formula: C15H13FO2

Categories: Active Pharmaceutical Ingredients > Antipyretic Analgesics

Flurbiprofen is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.Target: PGE synthaseFlurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraMore

Rocuronium bromide

CAS No: 119302-91-9

Formula: C32H53N2O4.Br

Categories: Active Pharmaceutical Ingredients > Anesthetic Agents

Crystallization; melting temperature of 161~169 °C. [α] D20 + 18.7 ° (C = 1.03, chloroform). Off-white SolidChEBI: The organic bromide salt of a 5alpha androstane compound having 3alpha-hydroxy-, 17beta-acetoxy-, 2beta-morpholino- and 16beta-N-allyllyrrolidinium subsituents.Rocuronium bromide is a short-acting nondepolarizing steroidal neuromuscularblocker introduced in the U.S.A as Zemuron and in the United Kingdom as Esmeron.k is indicated for use as an adjunct to general anesthesiaMore

Mifepristone

CAS No: 84371-65-3

Formula: C29H35NO2

Categories: Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Mifepristone is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay.More

Clozapine

CAS No: 5786-21-0

Formula: C18H19ClN4

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

Clozapine (HF 1854) is an antipsychotic used to treat schizophrenia. Clozapine is a potent antagonist of dopamine and a number of other receptors, with a Ki of 9.5 nM for M1 receptor. More

Cilostazol

CAS No: 73963-72-1

Formula: C20H27N5O2

Categories: Active Pharmaceutical Ingredients > Blood System Drugs

Cilostazol(OPC 13013; OPC 21) is a potent inhibitor of PDE3A, the isoform of PDE 3 in the cardiovascular system (IC50=0.2 uM).IC50 Value: 0.2 uM [1]Target: PDE3Ain vitro: Cilostazol caused a concentration-dependent increase in the cAMP level in rabbit and human platelets with similar potency. Furthermore, cilostazol and milrinone were equally effective in inhibiting human platelet aggregation with a median inhibitory concentration (IC50) of 0.9 and 2 microM, respectively. In rabbit ventrMore

(-)-Flurbiprofen

CAS No: 51543-40-9

Formula: C15H13FO2

Categories: Active Pharmaceutical Ingredients > Antipyretic Analgesics

Tarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [3H]9-cis-RA to RXRα LBD with IC50 of 75 μM. More

1119 Active Pharmaceutical Ingredients Suppliers

Short on time? Let Active Pharmaceutical Ingredients sellers contact you.

Vancomycin

CAS No: 1404-90-6

Formula: C66H75Cl2N9O24

Categories: Active Pharmaceutical Ingredients > Antibiotics

ChEBI: A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.Vancomycin is a complex tricyclic glycopeptide antibiotic produced by Streptococcus orientalis[1, 2]. Vancomycin was first discovered in the soil samples of the inner jungle of Borneo in the 1950s. Due to the presence of impurities, the use of vancomycin is greatly restricted.More

Phenylbutazone

CAS No: 50-33-9

Formula: C19H20N2O2

Categories: Active Pharmaceutical Ingredients > Antipyretic Analgesics

Phenylbutazone is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis.Target: OthersPhenylbutazone was originally made available for use in humans for the treatment of rheumatoid arthritis and gout in 1949. However, when combined with paracetamol and many other household painkillers even in the smallest doses can cause irreversible liver degradation proving fatal in many cases. It is no longer approved, and therefore notMore

(+)-Eplerenone

CAS No: 107724-20-9

Formula: C24H30O6

Categories: Active Pharmaceutical Ingredients > Circulatory System Drugs

White SolidEplerenone derives its antihypertensive effect by blocking the binding of aldosteroneat the mineralocorticoid receptor (MR). The drug, which was previously approvedonly for the oral treatment of hypertension, is now indicated to improve survival ofstable patients with left ventricular systolic dysfunction (ejection fraction <40%) andclinical evidence congestive heart failure (CHF) after an acute myocardial infarction.More

Idebenone

CAS No: 58186-27-9

Formula: C19H30O5

Categories: Active Pharmaceutical Ingredients > Antioxidant Ingredient

Idebenone is a synthetic variant of coenzyme Q10 (CoQ10), which initially developed for the treatment of Alzheimer's disease and other cognitive defects.Target: OthersIdebenone is a synthetic variant of coenzyme Q10 (CoQ10), which initially developed for the treatment of Alzheimer's disease and other cognitive defects. Idebenone was generally well tolerated with similar numbers of adverse events in each group. One child receiving high-dose idebenone developed neutropenia after 6 months,More

Bacitracin Zinc

CAS No: 1405-89-6

Formula: C66H101N17O16SZn

Categories: Active Pharmaceutical Ingredients > Antibiotics

Bacitracin Zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.Target: AntibacterialBacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. Its unique name derives from the fact that the bacillus producing it was first isolated in 1943 from a knee scrape from a girl named Margaret Tracy. As a toxic and difficult-tMore

Pitavastatin

CAS No: 147511-69-1

Formula: C25H24FNO4

Categories: Active Pharmaceutical Ingredients > Circulatory System Drugs

Pitavastatin (Brand Name: LIVALO) is an inhibitor of HMG-CoA reductase which catalyzes the first step of cholesterol synthesis. It appears as odorless and white to pale-yellow powder. It takes effects by reducing the level of certain fatty substances such as cholesterol in the body. Therefore, it is mainly indicated for the treatment of hypercholesterolaemia and for the prevention of cardiovascular diseases. It can not only lower the high cholesterol and triglyceride in certain patients, but alMore

Calcipotriol

CAS No: 112965-21-6

Formula: C27H40O3

Categories: Active Pharmaceutical Ingredients > Specialty Drugs

White Crystalline SolidCalcipotriol is a topical vitaminD3 derivative effective in the treatment of psoriasis vulgaris. The drug acts by binding to vitamin D3 receptors in the skin keratinocytes, producing an elevation in cell differentiation and a reduction in cell proliferation. Although its efficacy is comparable to calcitriol, calcipotriol exhibits at least 100 times less effect on calcium metabolism in rats.More

Tobramycin

CAS No: 32986-56-4

Formula: C18H37N5O9

Categories: Active Pharmaceutical Ingredients > Antibiotics

Tobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius.Target: AntibacterialTobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas [1]. Tobramycin works by binding to a site on the bacterial 30S and 50S ribosome, preventing formation of the 70S complex. As a result, mRNAMore

Sofosbuvir

CAS No: 1190307-88-0

Formula: C22H29FN3O9P

Categories: Active Pharmaceutical Ingredients > Antivirals

ChEBI: A nucleotide conjugate that is used in combination with ledipasvir (under the trade name Harvoni) for the treatment of chronic hepatitis C genotype 1 infection.Sofosbuvir is a drug used for the treatment of hepatitis C. It is recommended to be used in combination with other drugs (such as velpatasvir) for the first-line treatment for HCV genotypes 1, 2, 3, 4, 5, and 6. It takes effect through acting as a nucleotide analog inhibitor, being capable of specially inhibiting the HCV NS5B (nonMore

Active Pharmaceutical Ingredients Market

Market report will help you efficiently source API chemicals! ECHEMI can provide export and import data of API products you need to monitor and analyze the API market!
  • Phytosterol:

    40.0Yuan/kg -

Frequently Asked Questions

Are APIs safe to store and transport?

APIs must be handled according to regulatory and safety guidelines. Proper storage conditions, protective equipment, and transportation protocols are required to maintain stability and prevent contamination or hazards.

What industries use APIs?

APIs are widely used in pharmaceutical, veterinary, nutraceutical, and chemical research industries. They are essential for manufacturing medications, supplements, and experimental formulations.

How can I buy active pharmaceutical ingredients in bulk?

You can find certified API manufacturers and traders on ECHEMI. They provide detailed product information, CAS numbers, and safety data sheets (SDS) to ensure safe and reliable bulk purchases.

What are the top selling APIs on ECHEMI?

The top selling APIs on ECHEMI include Veterinary Raw Materials, Anesthetic Agents, Antiallergic Drugs, Feed Additives, Hormones and Endocrine Drugs, Digestive System Drugs, Vitamins and Minerals, Synthetic Anti-infective Drugs, Respiratory Drugs, and other chemical drugs.

What are active pharmaceutical ingredients?

Active Pharmaceutical Ingredients, also known as APIs, are the main active ingredients in a pharmaceutical drug to provide the intended therapeutic effect. APIs can be chemically synthesized or obtained from natural sources like plants and animals. After identifying the API, it is combined with other inactive ingredients to create a drug product that can be taken in different forms, such as tablets, capsules or injections.

What are the most common active pharmaceutical ingredients?

Here are some examples of common API chemicals.

1) Paracetamol (Acetaminophen) - a pain reliever and fever reducer

2) Ibuprofen - a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation

3) Aspirin - a medication used to reduce pain, fever, and inflammation and also used as a blood thinner

4) Amoxicillin - an antibiotic used to treat bacterial infections

5) Metformin - an oral medication for type 2 diabetes that lowers blood sugar levels

6) Omeprazole - a proton-pump inhibitor (PPI) used to reduce stomach acid production

7) Atorvastatin - a medication used to lower cholesterol levels in the blood

8) Sertraline - an antidepressant medication belonging to the class of selective serotonin reuptake inhibitors (SSRIs)

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.