Eu evaluation of the safety and efficacy of the diol dehydrating enzyme DSM 33625 as an additive for silage in all animals

On 21 February 2023, according to the European Union Food Safety Authority (EFSA), at the request of the European Commission, The EU Animal Feed Additives and Products (FEEDAP) Research Group has issued a scientific opinion on the safety and efficacy of Lentilactobacillus diolivorans DSM 33625 as an additive for silage in all animals.

After evaluation, the panel concluded that the additive is safe for the target species, consumers and the environment under the proposed conditions of use. The additive can prolong the aerobic stability of silage preparation from easy and moderately difficult silage materials (DM range 32-65%) at a minimum concentration of 1×108 CFU/kg feed. Some of the original reports are as follows:

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on Lentilactobacillus diolivorans (formerly Lactobacillus diolivorans) DSM 33625 when used as a technological additive to improve ensiling of forage. The additive is intended for use with all forages and for all animal species at a proposed minimum concentration of 1 × 108 colony forming units (CFU)/kg forage. The bacterial species L. diolivorans is considered by EFSA to be suitable for the qualified presumption of safety approach to safety assessment. As the identity of the strain has been clearly established and no acquired antimicrobial resistance determinants of concern were detected, the use of the strain as a silage additive is considered safe for livestock species, for consumers of products from animals fed the treated silage and for the environment. The additive is not a skin or an eye irritant. In the absence of data, no conclusion can be drawn on the skin sensitisation of the additive. Given the proteinaceous nature of the active agent, the additive should be considered a respiratory sensitiser. The FEEDAP Panel concluded that Lentilactobacillus diolivorans DSM 33625 at a minimum concentration of 1 × 108 CFU/kg forage may extend the aerobic stability of silage prepared from easy and moderately difficult to ensile forage material with a DM range of 32 -- 65%.