This product can directly penetrate the cell membrane into the body cells, activate pyruvate oxidase, so that cells in a low-energy and hypoxic state can continue to metabolize smoothly, and participate in the energy metabolism and protein synthesis of the human body.

This product can directly penetrate the cell membrane into the body cells, activate pyruvate oxidase, so that cells in a low-energy and hypoxic state can continue to metabolize smoothly, and participate in the energy metabolism and protein synthesis of the human body.

This product can directly penetrate the cell membrane into the body cells, activate pyruvate oxidase, so that cells in a low-energy and hypoxic state can continue to metabolize smoothly, and participate in the energy metabolism and protein synthesis of the human body.

This product can directly penetrate the cell membrane into the body cells, activate pyruvate oxidase, so that cells in a low-energy and hypoxic state can continue to metabolize smoothly, and participate in the energy metabolism and protein synthesis of the human body.

It is converted into flavine mononucleotide (FMN) and flavine adenine dinucleotide (FAD), both of which are important coenzymes for tissue respiration. It can also activate vitamin B6, convert tryptophan into niacin, and may be related to maintaining the integrity of red blood cells.

(1) Effects on water and electrolyte excretion. ① Diuretic effect, increased excretion of urinary sodium, potassium, chloride, phosphorus and magnesium, and decreased excretion of urinary calcium. The mechanism of action of this type of drug is mainly to inhibit the reabsorption of sodium chloride in the distal tubule anterior segment and the proximal tubule (less severe), thereby increasing the Na-K exchange in the distal tubule and the collecting duct, and increasing K+ secretion. Its mechanism of action is not yet fully understood. This type of drug can inhibit carbonic anhydrase activity to varying degrees, which can explain its effect on the proximal tubule. This type of drug can also inhibit phosphodiesterase activity, reduce the renal tubular uptake of fatty acids and mitochondrial oxygen consumption, thereby inhibiting the active reabsorption of Na and Cl- by the renal tubule. ② Antihypertensive effect. In addition to the diuretic and sodium excretion effects, there may be extrarenal mechanisms involved in antihypertensive effect, which may be to increase the excretion of Na in the gastrointestinal tract. (2) Effects on renal hemodynamics and glomerular filtration function. Due to the decrease in renal tubular reabsorption of water and Na, the increase in renal tubular pressure, and the increase in water and Na flowing through the distal convoluted tubule, the macula densa is stimulated through the tubular-glomerular reflex, which increases the secretion of renin and angiotensin in the kidney, causing renal vasoconstriction, decreased renal blood flow, contraction of the glomerular afferent and efferent arterioles, and decreased glomerular filtration rate. The decrease in renal blood flow and glomerular filtration rate, as well as the lack of effect on the loop of Henle, are the main reasons why this type of drug has a much inferior diuretic effect to loop diuretics.

By inhibiting phosphodiesterase, it increases intracellular cyclic adenosine monophosphate levels and relaxes bronchial smooth muscle

By inhibiting phosphodiesterase, it increases intracellular cyclic adenosine monophosphate levels and relaxes bronchial smooth muscle

By inhibiting phosphodiesterase, it increases intracellular cyclic adenosine monophosphate levels and relaxes bronchial smooth muscle

Relaxes bronchial smooth muscle by stimulating β-adrenergic receptors

Relaxes bronchial smooth muscle by blocking M cholinergic receptors

It inhibits the synthesis and release of prostaglandins in the hypothalamus, restores the normal responsiveness of the receptor neurons in the temperature regulation center, and has an antipyretic effect; it has an analgesic effect by inhibiting the synthesis of prostaglandins, etc.

It inhibits the synthesis and release of prostaglandins in the hypothalamus, restores the normal responsiveness of the receptor neurons in the temperature regulation center, and has an antipyretic effect; it has an analgesic effect by inhibiting the synthesis of prostaglandins, etc.

This product is a compound antipyretic analgesic. Aminopyrine and phenacetin can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal responsiveness of the receptor neurons in the temperature regulation center and play an antipyretic role; at the same time, it also plays an analgesic role by inhibiting the synthesis of prostaglandins.

This product is a compound antipyretic analgesic. Aminopyrine and phenacetin can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal responsiveness of the receptor neurons in the temperature regulation center and play an antipyretic role; at the same time, it also plays an analgesic role by inhibiting the synthesis of prostaglandins.