Anti-inflammatory drugs. A pharmacological experiment on a rat immune ulcerative colitis model was conducted to compare the effects of anal suppositories and oral tablets in the treatment of colitis. The results showed that the therapeutic effect of anal suppositories was significantly better than oral administration.

This product is a nitroimidazole derivative that can inhibit the redox reaction of amoeba and break the nitrogen chain of the protozoa. In vitro tests have shown that when the drug concentration is 1~2mg/L, the histolytica amoeba can undergo morphological changes in 6~20 hours and all are killed within 24 hours. When the concentration is 0.2mg/L, the histolytica amoeba can be killed within 72 hours. This product has a strong effect of killing trichomonas, and its mechanism is unknown. Metronidazole has a killing effect on cells and anaerobic microorganisms growing under hypoxic conditions. The metabolites generated when it is reduced in the human body also have anti-anaerobic effects, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and ultimately causing bacterial death.

This product is a derivative of ibufenac, and its analgesic, anti-inflammatory and antipyretic effects are 2-2.5 times stronger than indomethacin and 26-50 times stronger than aspirin. The analgesic and anti-inflammatory effects of this product are achieved by inhibiting cyclooxygenase to reduce prostaglandins and also by inhibiting lipoxygenates to reduce the products of leukotrienes, bradykinin, etc.

This product is a derivative of ibufenac, and its analgesic, anti-inflammatory and antipyretic effects are 2-2.5 times stronger than indomethacin and 26-50 times stronger than aspirin. The analgesic and anti-inflammatory effects of this product are achieved by inhibiting cyclooxygenase to reduce prostaglandins and also by inhibiting lipoxygenates to reduce the products of leukotrienes, bradykinin, etc.