Compound diatrizoate meglumine injection
Function and Efficacy
This product is a diagnostic drug. The sodium ion concentration of its 76% solution is about 136mmol/L, which is close to the concentration in plasma and has little effect on myocardial cell function. Sodium diatrizoate Sodium diatrizoate is an ionic monomer iodine contrast agent. Iodine can absorb a large amount of X-rays. After being injected into the body, it forms a density contrast with the surrounding tissues under X-rays and develops. When using the direct introduction method for contrast imaging, it can be directly injected into the blood vessels or other cavities to show the luminal morphology. When using the physiological absorption method for contrast imaging, the contrast agent injected into the blood vessels can enter the diseased tissue through the damaged vascular endothelium or the damaged blood-brain barrier to show the lesions. The urinary tract morphology can be displayed when excreted through the kidneys. Diatrizoate meglumine; same as sodium diatrizoate.
Ingredients
60% contains 292mg/ml iodine, and 76% contains 370mg/ml iodine.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Diatrizoate sodiumIngredients |
This product is a diagnostic drug. The sodium ion concentration of its 76% solution is about 136mmol/L, which is close to the concentration in plasma and has little effect on myocardial cell function. Sodium diatrizoate is an ionic monomer iodine contrast agent. Iodine can absorb a large amount of X-rays. After being injected into the body, it forms a density contrast with the surrounding tissues under X-rays and develops. When using the direct introduction method for contrast imaging, it can be directly injected into the blood vessels or other cavities to show the luminal morphology. When using the physiological absorption method for contrast imaging, the contrast agent injected into the blood vessels can enter the diseased tissue through the damaged vascular endothelium or the damaged blood-brain barrier to show the lesions. The urinary tract morphology can be displayed when excreted through the kidneys. More |
737-31-5 | 5 |
Indication
It is suitable for urinary tract angiography, cardiac angiography, cerebral angiography, angiography of other organs and peripheral blood vessels, CT enhanced scanning and various other cavity and fistula angiography, and can also be used for coronary angiography.
Usage and Dosage
1 Cardiovascular angiography or aortic angiography is injected into the heart cavity through a catheter. The usual dosage for adults is 40-60 ml (76%), or 1 ml/kg according to body weight, injected with a pressure syringe in about 2 seconds. When repeated injections or other angiography are performed simultaneously, the total amount should not exceed 225 ml. The usual dosage for children is 1.0-1.5 ml/kg (76%) according to body weight, and the total amount of repeated injections should not exceed 4 ml/kg. Infants and young children should not exceed 3 ml/kg. 2 Coronary angiography is injected through a catheter. The usual dosage for adults is 4-10 ml (76%) at a time. Repeated injections are allowed and the injection must be performed under electrocardiogram monitoring. 3 Cerebral angiography is injected into the common carotid artery through a catheter. The usual dosage for adults is 10 ml (60%) at a time, and the injection speed should not exceed 5 ml per second.
Adverse Reactions
Reactions such as nausea, vomiting, salivation, dizziness, and urticaria may occur.
Precautions
1. Patients who are allergic to iodine are contraindicated to use this product. 2. Patients with impaired liver and kidney function, active pulmonary tuberculosis, multiple spinal cord tumors and hyperthyroidism are contraindicated to use this product. 3. Patients with homocystinuria should not undergo angiography, otherwise it may cause thrombosis or embolism. 4. This product is strictly prohibited to be injected into the ventricles, intracranial space, intraspinal subarachnoid space, cystic cavity and fistula communicating with the subarachnoid space.
Drug Interactions
1. Intravascular injection of this product immediately after taking cholecystography contrast agent will increase the toxic effect on the kidneys, especially in patients with impaired liver function. 2. Although the use of vasopressors during aortic angiography can improve the contrast of the imaging, due to the contraction of visceral blood vessels, a large amount of contrast agent is forced to enter the spinal cord blood vessels, which increases the neurotoxicity of this product and may cause paraplegia. 3. This product should not be mixed with antihistamines for injection. It may precipitate when mixed with promethazine hydrochloride, diphenhydramine hydrochloride, chlorpheniramine maleate (chlorpheniramine), etc.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
20ml:12g
Manufacturer
Xi`an Han Feng Pharmaceutical Co., Ltd.
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Founded in:
2003-03-11 -
Address:
No. 15, Wenji Road, Lantian County Industrial Park -
Tax NO.:
91610122742829723D -
Registered Funds:
25 million yuan -
Email: