Limaprost Tablets

The active ingredient is limaprost

White flakes

Improve the subjective symptoms (lower back and lower limb pain and numbness) of patients with degenerative lumbar spinal stenosis (normal straight leg raising test and intermittent claudication).

Adults usually take 5 μg orally three times a day.

Adverse reactions: 1. Adverse reactions of the original limaprost in foreign clinical trials: 34 patients (9.1%) out of 373 patients had 54 adverse reactions (including abnormal clinical examination values). The main adverse reactions were 8 cases of stomach discomfort (2.1%), 6 cases of rash (1.6%), 4 cases of headache and heaviness of the head (1.1%), 4 cases of diarrhea (1.1%), and 3 cases of anemia (0.8%). 2. Adverse reactions of the original limaprost after its launch abroad: 136 patients (5.8%) out of 2327 patients had 169 adverse reactions (including abnormal clinical examination values). The main adverse reactions were 34 cases of stomach and abdominal discomfort (1.5%), 13 cases of abdominal pain (0.6%), 10 cases of diarrhea (0.4%), 10 cases of headache (0.4%), 7 cases of nausea (0.3%), and 7 cases of heartburn (0.3%). 3. Serious adverse reactions Liver dysfunction, jaundice Since liver dysfunction and jaundice (incidence unknown※) may occur with significant increases in AST and ALT, sufficient observation is required. When abnormalities are confirmed, appropriate measures such as discontinuation of medication should be taken. 4. Other adverse reactions: 0.1% to 1% 0.1% Incidence unknown * Hypersensitivity reaction Note 1 Rash, itching, etc. Urticaria Photosensitivity Bleeding tendency Note 2 Bleeding Blood Anemia, thrombocytopenia Gastrointestinal tract Diarrhea, nausea, abdominal discomfort, abdominal pain, loss of appetite, heartburn Vomiting, bloating, thirst, oral mucositis Tongue numbness Liver AST, ALT increase and other liver function abnormalities Circulatory system Palpitations Tachycardia, hypotension, acrocyanosis, increased blood pressure Psychoneural system Headache, dizziness Numbness, drowsiness, insomnia Others Hot flushes, fever General weakness, chest pain, chest discomfort, limb pain, edema, breast swelling, tremors, lower limb hairiness, abnormal taste ※: Derived from spontaneous reports, so the incidence is unknown. Note 1): When it occurs, take appropriate measures such as stopping the medication. Note 2): Observe thoroughly and stop the medication when abnormality is confirmed.

1. It is contraindicated for people who are allergic to any ingredient in this product. 2. It is contraindicated for women who are pregnant or may become pregnant.

Precautions for children: The safety of limaprost for children has not been established (no experience of use). Precautions for pregnancy and lactation: Pregnant women or women who may become pregnant are prohibited from using limaprost. In animal experiments, limaprost showed uterine contraction, and the safety of limaprost during pregnancy has not yet been determined. Precautions for the elderly: Foreign clinical data show that there is no significant difference in drug safety and effectiveness between elderly patients and non-elderly patients using this product.

Limaprost inhibits platelet aggregation, and its effect may be enhanced when used in combination with drugs with similar efficacy. Therefore, when used in combination with antiplatelet drugs (such as aspirin, ticlopidine, cilostazol, etc.), thrombolytic drugs (such as urokinase, etc.), and anticoagulants (such as heparin sodium, warfarin, etc.), it may increase the tendency of bleeding. Patients should be carefully observed and the dosage should be adjusted.

Seal tightly and store at a temperature not exceeding 30°C.

5µg

24 months. This product is sensitive to moisture and should be used as soon as possible after tearing open the polyester/aluminum/polyester/polyethylene medicinal composite bag, and the opened medicine should be discarded after more than 20 days.

Beijing Tide Pharmaceutical Co., Ltd.

• Founded in:

  1995-05-29

• Address:

  No. 8 Rongjing East Street, Beijing Economic and Technological Development Zone, Beijing

• Tax NO.:

  911103026000314683

• Registered Funds:

  500 million yuan

• Website:

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