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Etofenamate cream

Function and Efficacy

This product is a non-steroidal anti-inflammatory drug for external use on the skin, and is a derivative of anthranilic acid. It mainly acts on various stages of the inflammatory process. In addition to inhibiting the synthesis of prostaglandins, it also inhibits the release of histamine, has a neutralizing effect on bradykinin and 5-hydroxytryptamine, and inhibits complement activity and the release of hyaluronidase. Toxicological effects: In chronic toxicity studies, rats (7.0, 27.0, 100.0 mg/kg) and monkeys (7.0, 26.0, 100.0 mg/kg) were given daily oral administration of etofenamate (for 1 year). Its ineffective dose (27.0 mg/kg for rats and 26.0 mg/kg for monkeys) is much higher than the daily therapeutic dose for humans. Further studies have shown that this drug has no evidence of teratogenic, mutagenic and carcinogenic effects. Reproductive toxicity: Etofenamate cream can pass the placental barrier. After lactating women took etofenamate orally, etofenamate was not detected in breast milk, but its main metabolite flufenamic acid was detected. However, the concentrations are far below the therapeutic dose and therefore have no important practical significance.

Ingredients

The main ingredient of this product is etofenamate.

Name Description Content CAS NO. Manufacturer
EtofenamateIngredients

This product is a non-steroidal anti-inflammatory drug for external use on the skin and is a derivative of anthranilic acid. It mainly acts on various stages of the inflammatory process. In addition to inhibiting the synthesis of prostaglandins, it also inhibits the release of histamine, has a neutralizing effect on bradykinin and 5-hydroxytryptamine, and inhibits complement activity and the release of hyaluronidase.

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30544-47-9 8

Appearance

This product is a white cream with an emulsion base and a slight odor of benzaldehyde.

Indication

1. Rheumatism of soft tissues such as the musculoskeletal system. 2. Muscular rheumatism. 3. Muscle stiffness with frozen shoulder (periarthritis of shoulder). 4. Lumbar pain. 5. Sciatica. 6. Tenosynovitis. 7. Bursitis. 8. Injuries caused by excessive tension and erosion of the spine or joints (spondylosis, osteoarthritis). 9. Contusions (such as sports injuries). 10. Bumps. 11. Sprains. 12. Strain.

Usage and Dosage

Depending on the size of the painful area, apply 1-2g (5-10cm) each time, 3-4 times a day, apply to the painful area and massage gently, or follow the doctor's advice.

Adverse Reactions

1. In rare cases, skin redness may occur. 2. In rare cases, skin allergic reactions may occur (e.g., severe itching, rash, erythema, swelling, blisters, etc.). The above symptoms usually subside quickly after discontinuation of the drug.

Precautions

It is contraindicated for patients who are allergic to etofenamate, flufenamic acid and other non-steroidal anti-inflammatory drugs.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

When used correctly, Umab has not been found to interact with other drugs.

Storage

Airtight, it is recommended to store below 25℃. The validity period is tentatively set at three years.

Packaging Specification

40g:4g

Validity Period

Tentative 36 months

Manufacturer

Bayer Healthcare Company Ltd.

  • Founded in:

    1995-08-25
  • Address:

    No. 7 Rongjing East Street, Beijing Economic and Technological Development Zone, Beijing
  • Tax NO.:

    91110302600035733E
  • Registered Funds:

    $105.97 million
  • Website:

  • Email:

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