Omeprazole enteric-coated capsules
Function and Efficacy
1. Proton pump inhibitor. 2. This product is a fat-soluble weak alkaline drug, which is easily concentrated in an acidic environment. Therefore, after oral administration, it can be specifically distributed in the secretory tubules of the gastric mucosal parietal cells, and converted into the active form of sulfenamide in this high-acid environment, and then irreversibly combined with the sulfhydryl group of the H, K-ATPase (also known as the proton pump) in the secretory membrane of the parietal cells through a disulfide bond to form a complex of sulfenamide and the proton pump, thereby inhibiting the activity of the enzyme and blocking the final step of gastric acid secretion. Therefore, this product has a strong and lasting inhibitory effect on gastric acid secretion caused by various reasons.
Ingredients
The main ingredient of this product is omeprazole.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| OmeprazoleIngredients |
Proton pump inhibitor. This product is a fat-soluble weakly alkaline drug that is easily concentrated in an acidic environment. Therefore, after oral administration, it can be specifically distributed in the secretory tubules of the gastric mucosal parietal cells and converted into the active form of sulfenamide in this high-acid environment. Then, it irreversibly combines with the sulfhydryl group of the H, K-ATPase (also known as the proton pump) in the secretory membrane of the parietal cells through a disulfide bond to form a complex of sulfenamide and the proton pump, thereby inhibiting the activity of the enzyme and blocking the final step of gastric acid secretion. Therefore, this product has a strong and lasting inhibitory effect on gastric acid secretion caused by various reasons. More |
73590-58-6 | 83 |
Indication
It is suitable for gastric ulcer, duodenal ulcer, stress ulcer, reflux esophagitis and Zollinger-Ellison syndrome (gastrinoma).
Usage and Dosage
Oral administration, do not chew. 1. Peptic ulcer: 20 mg (1 tablet at a time), 1-2 times a day. Swallow in the morning or once in the morning and evening. The treatment course for gastric ulcer is usually 4-8 weeks, and the treatment course for duodenal ulcer is usually 2-4 weeks. 2. Reflux esophagitis: 20-60 mg (1-3 tablets at a time), 1-2 times a day. Swallow in the morning or once in the morning and evening. The treatment course is usually 4-8 weeks. 3. Zollinger-Ellison syndrome: 60 mg (3 tablets at a time), once a day. The total daily dose can be adjusted to 20-120 mg (1-6 tablets) according to the condition. If the total daily dose needs to exceed 80 mg (4 tablets), it should be taken in two doses.
Adverse Reactions
1. This product is well tolerated. Common adverse reactions include diarrhea, headache, nausea, abdominal pain, flatulence and constipation. Occasionally, serum aminotransferase (ALT, AST) increases, rash, dizziness, drowsiness, insomnia, etc. are observed. These adverse reactions are usually mild, disappear automatically, and are not related to the dose. 2. No serious adverse reactions have been observed in long-term treatment, but gastric mucosal cell hyperplasia and atrophic gastritis may occur in some cases.
Precautions
1. It is forbidden for those who are allergic to this product, and should be used with caution by those with allergic constitution; 2. It should be used with caution by pregnant and lactating women; 3. It is forbidden for infants and young children.
Special Population Medication
Precautions for children: Not for use in infants and young children. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: Not yet clear.
Drug Interactions
This product can delay the elimination of drugs metabolized by the liver in the body, such as diazepam, phenytoin sodium, warfarin, nifedipine, etc. When this product is used together with the above-mentioned drugs, the dosage of the latter should be reduced.
Storage
Keep away from light, sealed and stored in a dry place.
Packaging Specification
10mg
Validity Period
24 months.
Manufacturer
Shanghai Meiyou Pharmaceutical Co., Ltd.
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Founded in:
1998-02-26 -
Address:
No. 1388, Wusi Road, Fengxian District, Shanghai -
Tax NO.:
91310120134051612H -
Registered Funds:
64.8 million yuan -
Email: