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Supply 99% Repaglinide Powder CAS 135062-02-1

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CAS No.:

135062-02-1

Grade:

Pharmaceutical grade

Content:

99%

Port:

Xi'an

Brand:

TGY

Packaging:

1kg/foil bag,25kg/Cardboard Drum

Price valid (until):

2023-07-31

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Xi'an Tian Guangyuan Biotech Co., Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Minoxidil,Paracetamol,Diclofenac sodium,fenbendazole,Ivermectin

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Product Description
Seller Information

Description

Product Detail

Product name	Repaglinide
Cas number	135062-02-1
Appearance	White powder
MF	C27H36N2O4
MW	452.58600

Repaglinide, a type of medicines for treating diabetes, is insulinotropic agent which belongs to the non-sulfonylurea. It was developed by Boehringer Ingelheim from Germany, and won approval by FDA from the United States in December 1997. In 1998, it was successively listed in the United States and European countries, with commodity name as NovoNorm. Mainly used in the clinical treatment of type diabetes (non-insulin-dependent) patients whose hyperglycemia can't be effectively controlled via diet, weight loss and exercise.

Function & Application

Repaglinide lowers blood glucose by stimulating the release of insulin from the pancreas.
Repaglinide achieves this by closing ATP-dependent potassium channels in the membrane of the beta cells. This depolarizes the beta cells, opening the cells' calcium channels, and the resulting calcium influx induces insulin secretion.

Certificates

Basic Info

Product Name:

Repaglinide

Other Name:

Benzoic acid,2-ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]-;Benzoic acid,2-ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]-,(S)-;2-Ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid;Repaglinide;AG-EE 623ZW;Prandin;NovoNorm;(S)-(+)-2-Ethoxy-4-[[[N-[1-(2-piperidinophenyl)-3-methylbutyl]amino]carbonyl]methyl]benzoic acid;AGEE 623;Novolon;Eurepa;(S)-(+)-Repaglinide;GlucoNorm;Europa 0.5;Europa 1;(S)-2-Ethoxy-4-[2-[[3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid;Enyglid

CAS No.:

135062-02-1

Molecular Formula:

C27H36N2O4

InChIKeys:

InChIKey=FAEKWTJYAYMJKF-QHCPKHFHSA-N

Molecular Weight:

452.59

Exact Mass:

452.59

EC Number:

1312995-182-4

UNII:

668Z8C33LU

NSC Number:

759893

DSSTox ID:

DTXSID3023552

NCI Thesaurus Code:

C47703

ATC Code:

A10BX02|A - Alimentary tract and metabolism

HScode:

2933399090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

78.9

XLogP3:

5.9

Appearance:

white solid

Density:

1.137±0.06 g/cm3(Predicted)

Melting Point:

132 °C

Boiling Point:

672.9°C at 760 mmHg

Flash Point:

360.8ºC

Refractive Index:

1.567

Water Solubility:

DMSO: 34 mg/mL

Storage Conditions:

2-8°C

Vapor Pressure:

5E-19mmHg at 25°C

Toxicity:

LD50 orally in rats: >1 g/kg (Grell)

Specific rotation:

D20 +6.97° (c = 0.975 in methanol); D20 +7.45° (c = 1.06 in methanol)

See More Repaglinide Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 2

Reproductive toxicity, Additional category for effects on or via lactation

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H361 Suspected of damaging fertility or the unborn child H362 May cause harm to breast-fed children H412 Harmful to aquatic life with long lasting effects
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P263 Avoid contact during pregnancy and while nursing. P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment.
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Repaglinide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Minoxidil,Paracetamol,Diclofenac sodium,fenbendazole,Ivermectin

Location:
I-City unit 3, South of Tangyan Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
51-100

Year of Establishment:
2015

Certifications:
HACCP,Halal,GMP,ISO

Company Profile

XI'AN TIANGUANGYUAN BIOTECH CO., LTD. is specialized in researching, producing and selling Herbal Extract and API powder, which are mainly used in nutraceutical, cosmetic, beverage and Food Additives etc. Owing plant base, extracting and purifying in GMP workshop, concentrating on the quality and cost each link. It is aiming of benefiting the world with lowest price but best products.We are keeping overcritical on the quality and persisting in the profession all the time. TGY owns two standardized production workshops, advanced multi-function extractors and juice concentrate equipment, covering 12,000㎡ annual dried material processed 950MT, monthly production ability 60MT. 32 scientists are in R&D team. We have strict QC standards and perfect quality guarantee system, GMP certified, also FDA, ISO9001 and Halal certified. We also build an integrative marketing center in Xi'an city, China, involving in research, test, sale and service.

So far, we have 10 years experience for export in this field and have good relationship with regular customers from countries and regions in the world. Our company has got independent Import & Export License and has built good relationship with international expresses, as well as some air and sea shipping agents to provide timely and professional service for all clients.

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