JNJ-38877605
943540-75-8
99%
2026-07-26
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName JNJ-38877605 Cat No CEI-0039 Description JNJ-38877605 is a small-molecule, ATP-competitive inhibitor of the catalytic activity of c-Met. CAS No 943540-75-8 Molecular Weight 377.35 Purity >99% Storage 2 years at -20 centigrade Targets c-Met Molecular Formula C19H13F2N7 Chemical Name 6-(difluoro(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline Solubility DSMO 15 mg/mL Water In vitro JNJ-38877605 is a small-molecule, ATP-competitive inhibitor of the catalytic activity of c-Met. JNJ-38877605 showed around 600-fold selectivity for c-Met compared with a panel of 250 diverse tyrosine and serine-threonine kinases and was found to potently inhibit HGF-stimulated and constitutively activated c-Met phosphorylation in vitro. category Inhibitors(c1514) cas_num 943540-75-8 Basic Info-
Product Name:
6-[Difluoro[6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline
Other Name:Quinoline,6-[difluoro[6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]methyl]-;6-[Difluoro[6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline;JNJ 38877605;1072116-03-0
CAS No.:943540-75-8
Molecular Formula:C19H13F2N7
InChIKeys:InChIKey=JRWCBEOAFGHNNU-UHFFFAOYSA-N
Molecular Weight:377.357
Exact Mass:377.35
UNII:15UDG410PN
DSSTox ID:DTXSID20677253
HScode:2933990090
Categories:
Characteristics-
PSA:
73.8
XLogP3:2.1
Density:1.5±0.1 g/cm3
Refractive Index:1.734
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product