AV-412
451492-95-8
95%
2026-06-28
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName AV-412 Cat No CEI-1086 Description AV-412 is an orally bioavailable dual kinase inhibitor with potential antineoplastic activity. It binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2). Abbr AV-412(EGFR, ERBB2) Alias ERBB, ERBB1, HER1, PIG61, Mena Product Overview Inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) CAS No 451492-95-8 Molecular Weight 507 Purity > 95% Stability 2 years -20 centigrade Powder1 month -4 centigrade in DMSOMore than one month -80 centigrade in DMSO Storage -20 centigrade Synonyms ERBB, ERBB1, HER1, PIG61, Mena Targets EGFR, HER2 Molecular Formula C27H28ClFN6O Chemical Name N-(4-(3-chloro-4-fluorophenylamino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-ynyl)quinazolin-6-yl)acrylamide Solubility DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL category Specialty Chemicals(c26) cas_num 451492-95-8 Basic Info-
Product Name:
AV-412
Other Name:AV-412;MP-412;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-2-propenamide;2-PropenaMide,N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[3-Methyl-3-(4-Methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-;AV-412(freebase);N-(4-((3-chloro-4-fluoroChemicalbookphenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinazolin-6-yl)acrylamide;N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quin;N-[4-(3-chloro-4-fluoroanilino)-7-[3-methyl-3-(4-methylpiperazin-1-yl)but-1-ynyl]quinazolin-6-yl]prop-2-enamide
CAS No.:451492-95-8
Molecular Formula:C27H28ClFN6O
InChIKeys:ZAJXXUDARPGGOC-UHFFFAOYSA-N
Molecular Weight:507
Exact Mass:506.1997154
UNII:41OXH4FE7B
DSSTox ID:DTXSID10196403
Categories:
Characteristics-
PSA:
73.4
XLogP3:4.5
Density:1.33
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product