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Betaine Hcl | CAS 590-46-5 | Supports Liver & Osmotic Balance

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Unit Price:

$1000-1200/MT EXW

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CAS No.:

590-46-5

Grade:

feed grade, food grade, pharma grade

Content:

98%

Packaging:

25kg/bag /drum/ carton

Price valid (until):

2027-03-18

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PREMIUM INGREDIENT CO.,LTD

Company Type:

Manufactory

Location:

United Kingdom

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

80 days

Qualification:

Main Products:

l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate

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Product Description
Seller Information
Inquiry History

Description

Basic Information

Item	Betaine Hydrochloride
Product Name	Betaine Hcl
CAS No.	590-46-5
Appearance	White crystalline powder
Odor & Taste	Sour taste, odorless
Purity	≥98%
Moisture	≤1.0%
pH (1% solution)	1.0–3.0
Solubility	Easily soluble in water
Hygroscopicity	Low
Product Grade	Food grade, Feed grade
Main Application	Feed additive, food additive
Strength Positioning	Hydrochloride salt form, acidic property

Product Overview

Betaine Hydrochloride, as a natural trimethylglycine compound, acts as a critical methyl donor and osmoprotectant in human and animal metabolism. It effectively supports liver detoxification, maintains cellular osmotic pressure balance, and improves nutrient utilization efficiency.

Betaine Hydrochloride (Betaine HCl) — Acidic form of trimethylglycine. Available in feed grade (95%–97%) for animal nutrition and high-purity grade (98%) for digestive health supplements.

Character

1.Three types of betaine for different formulation requirements

2.High purity crystalline powder, stable quality for large bulk orders

3.Good water solubility, easy to add into powder, tablet and capsule formulas

4.Different hygroscopicity and pH characteristics to match diversified application scenarios

5.Available for food, dietary supplement and animal feed industries

Main Functions

Shared Functions ( betaine anhydrous, monohydrate &Hcl)

Methyl Donor — Betaine is an efficient methyl donor that supports normal methylation metabolism in animals and humans.

Cellular Osmoprotection — Acts as an osmolyte to stabilize cell structure, protect cells against dehydration and environmental stress.

Growth & Performance Support (Feed) — Helps improve feed conversion rate, nutrient utilization and overall growth performance in livestock and aquaculture.

Specific Functions

Function	Betaine Anhydrous	Betaine Monohydrate	Betaine HCl
Methyl donor & osmoprotectant	✅	✅	✅
Feed conversion & growth promotion	✅	✅	✅ (feed grade)
Gastric acid support / digestion aid	—	—	✅ (98% grade)
Food additive (texture & taste modifier)	✅	✅	—

Applications

1.Animal Feed (largest market for betaine anhydrous, monohydrate &Hcl)

Betaine HCl (feed grade) Used in feed formulations as both a methyl donor and an attractant/palatability enhancer, especially in aquafeed. Its acidic property also supports gastric health in young animals.

2. Food

Betaine HCl: Not typically used in food applications.

3. Dietary Supplement

Betaine HCl : Formulated into digestive health supplements to support gastric acid level and assist protein digestion.

Packaging & Storage

Packaging: 25kg food-grade bag / fiber drum, customized packaging available

Storage: Store in cool, dry, dark and ventilated warehouse, keep tightly sealed, Avoid moisture, high temperature and direct sunlight

Shelf Life: 24 months under sealed and proper storage conditions

Index	Betaine hydrochloride
Content	≧97.0%	≧98.0%	≧98.0%
Loss on drying	≤1.0%	≤0.5%	≤1.0%
Burning residue	≤1.5%	≤0.2%	≤1.0%
Heavy metal	≤0.001%	≤0.001%	≤0.001%
Arsenic	≤0.0001%	≤0.0001%	≤0.0001%
Trimethylamine residue	≤300ppm	≤300ppm	≤300ppm

ECHEMI Editorial Reference

Betaine hydrochloride is a natural compound found in many foods and also an active methyl-donor which can maintain normal DNA methylation patterns.
Betaine Hydrochloride is the hydrochloride form of betaine, a crystalline alkaloid occurring in sugar beets and other plants. Betaine, acting as a transmethylating metabolic intermediate, is the oxidation product of choline. Betaine hydrochloride is used as a gastric acidifier supplement.|A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)
Betaine hydrochloride is a vitamin-like substance that is a source of hydrochloric acid and aids the production of stomach acid. Gastric acid also helps protect the gastrointestinal tract from harmful bacteria. A normal level of gastric acid in the stomach—100,000-1,000,000 times more acidic than water—is sufficient to destroy bacteria, but some people produce deficient amounts of stomach acid, a condition that may lead to bacterial and parasitic infections of the intestines.One study showed that fasting people with normal gastric acid levels in the stomach had almost no bacteria in the small in- testine, while individuals with low levels of hydrochloric acid had some bacterial colonization in the stomach.Betaine hydrochloride is therefore recommended by some medical practitioners to sustain a healthy and normal production of stomach acid, especially to those that suffer from disorders such as allergies and asthma.Betaine hydrochloride is a synthesized chemical, and is not obtained from any plant or animal source. Gastric acid is produced by stomach cells, and is not available from any food source. Occasionally, betaine (C5H11NO2 )is recommended to reduce blood levels of homocysteine, which is associated with heart disease. This form of betaine is different from betaine hydrochlo- ride, and is available only with a doctor’s prescription.
colorless to white crystals
Betaine(trimethyl glycine) is an osmoprotectant, which is highly effective than proline. It is formed in fromcholine. Betaineis usually present in grains, spinach, beets,broccoli, shellfish and marine algae.

Basic Info

Product Name:

Betaine hydrochloride

Other Name:

Betaine Hydrochloride, AR;acidolhydrochloride;Acidol-Pepsin;Acinorm;Acipepsol;Aciventral forte;aciventralforte;Ammonium, (carboxymethyl)trimethyl-, chloride

CAS No.:

590-46-5

Molecular Formula:

C5H12ClNO2

InChIKeys:

HOPSCVCBEOCPJZ-UHFFFAOYSA-N

Molecular Weight:

153.61

Exact Mass:

153.05600

BRN:

3916181

EC Number:

209-683-1

UNII:

JK8U8K4D6K

NSC Number:

758207|32191|3976

TSCA:

TSCA listed

DSSTox ID:

DTXSID0044446

NCI Thesaurus Code:

C82301

Color/Form:

Colorless to white

ATC Code:

A16AA06|A - Alimentary tract and metabolism

HScode:

29239000

Categories:

Enzyme

Characteristics

PSA:

37.30000

XLogP3:

-3.21880

Appearance:

colorless to white crystals

Density:

1.29[at 20℃]

Melting Point:

241-242 °C(lit.)

Water Solubility:

64.7 g/100 mL (25 ºC)

Storage Conditions:

Store in a cool, dry place. Store in a tightly closed container.

Vapor Pressure:

0Pa at 25℃

Flammability characteristics:

Not classified

PH:

1 (50g/l, H2O, 20℃)

Collision Cross Section:

122.5 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Autoignition Temperature:

400 °C

Critical Temperature & Pressure:

room temp

See More Betaine hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Serious eye damage, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H318 Causes serious eye damage
Prevention	P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Betaine hydrochloride Safety Data Sheet 

Seller Information

Business Type: Manufactory
Main Products: l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate
Location: dongsheng road
Payment Terms: TT against copy of documents,L/C
Average lead Time: 80 days
Total Annual Revenue: $5 million-$10 million
Total Employees: 5-10
Year of Establishment: 2015

Premium Ingredient specializes in supplying and distributing food & feed amino acids, food additives and functional ingredients for more than a decade.

Our food additives portfolio covers phosphates, acidulants, preservatives, sweeteners, thickeners and leavening agents.

Our functional ingredients include vitamins, mineral products, botanical extracts, nutraceutical ingredients, functional fibers & bulking agents.

We serve over 100 clients across food & beverage, dietary supplement, sports nutrition, personal care, pharmaceutical and animal feed sectors, with products exported to dozens of countries worldwide. All our goods are sourced from top-tier Chinese manufacturers with proven expertise and complete management systems.

◆Amino Acids	◆ phosphates	◆ acidulants
◆ preservatives	◆ sweeteners	◆ functional fiber&bulking agent
◆ thickeners	◆ Leavening agents	◆ mineral products
◆ Botanical extracts	◆ vitamins	◆ nutritional products

Backed by over 10 years of industry experience, we provide one-stop-shop solutions combining high-grade products, prompt communication, on-time delivery and real-time market intelligence. Thanks to our long-term deep-rooted partnerships with source manufacturers, we can guarantee sufficient inventory, stable pricing and fast shipment.

Our third-party certifications include ISO9001, ISO14001, HACCP, HALAL, KOSHER, GMP, FAMI-QS and more. You can count on Premium Ingredient as your trusted global raw material supplier.

------------------------------------- Mission------------------------------------

Acting as a bridge between reliable Chinese manufacturers and global buyers, we carefully select partner factories with mature production capabilities and sound management systems. We deliver not only premium-quality raw materials, but also value-added services including market trend updates, supply chain risk alerts, product formulation consultation, consolidated sample shipment and full document support for import compliance. We timely forward overseas customers’ requirements to our partner factories to support product upgrading and achieve mutual growth.

-------------------------------------Our Quality------------------------------------

Our Quality

As a professional ingredient supplier, we do not operate manufacturing facilities. Instead, we build robust quality‑assurance workflows across our whole supply chain to safeguard consistent product performance for every shipment

Strict Supplier Due‑Diligence

Before entering any partnership, we carry out on-site factory visits and assess industry reputation, followed by multi-stage qualification reviews. We validate production qualifications, export track records, quality management systems and complete certification packages. New suppliers must pass sample evaluation, and only fully vetted top-tier factories are admitted to our approved supplier pool

Batch‑by‑batch Document Verification

For every order, we cross‑check factory‑issued test documents against agreed specifications including FCC, USP, EP, AJI, CP or your customized requirements. We will not forward documents to customers until key indicators are fully aligned with specifications. This step avoids inconsistent or mismatched documentation common in raw‑material trade.

Independent Third‑party Testing Coordination

Upon client request, we can arrange independent laboratory inspections from recognized third‑party institutions. We manage sample delivery, test protocol communication and report follow‑up to support your market compliance needs.

Quality Closure & Continuous Improvement

We keep traceable records for all delivered batches. If any quality concern arises, we act as your single point‑of‑contact to trace root causes with source factories, drive corrective actions and deliver practical resolution plans. Client feedback is systematically collected to optimize our supplier management and document‑review procedures.

We provide a comprehensive set of compliance documents to support your import and registration work. Our available documentation includes but is not limited to:

★ ISO Certification ★ Halal Certificate

★ Kosher Certificate ★ IP certificate

★ Haccp certificate ★ Allergens with Glutens

★ GRAS Statement ★ HACCP Program

★ BSE/TSE Statement ★ Certificate of Analysis

★ Country of Origin Certificate ★ Material Safety Data Sheet

★ Flow Chart (product processing) ★ Food Grade Certificate

★ Nutritional Information ★ GMO Statement

★ Specification Sheet

Inquiry History