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Home > Pharmaceutical Intermediates > Antiparasitics > Mebendazole for Sale > Mebendazole CAS No.: 31431-39-7 Grade: Pharmaceutical grade
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Mebendazole CAS No.: 31431-39-7 Grade: Pharmaceutical grade

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Unit Price: Get Latest Price
CAS No.:

31431-39-7

Grade:

Pharmaceutical Grade

Content:

99%

Port:

ANY PORT IN CHINA

Brand:

EAST CHEMSOURCES LIMITED

Packaging:

25kg/drum

Price valid (until):

2024-06-29

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Food additives,Pharmaceutical raw materials,Chemicals,Comestic raw materials

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Shop China Manufacturer Supply High Purity MEBENDAZOLE CAS 31431-39-7-Detailed Image 1

    SAFETY DATA SHEETS

    According to the UN GHS revision 9

    Version: 1.0

    Creation Date: July 15, 2019

    Revision Date: July 15, 2019

    SECTION 1: Identification

    1.1GHS Product identifier

    Product name

    Mebendazole

    1.2Other means of identification

    Product number

    -

    Other names

    mebenvet; Methyl (5-benzoyl-1H-benzo[d]imidazol-2-yl)carbamate; telmin

    1.3Recommended use of the chemical and restrictions on use

    Identified uses

    Industrial and scientific research use.

    Uses advised against

    no data available


    SECTION 2: Hazard identification

    2.1Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    2.2GHS label elements, including precautionary statements

    Pictogram(s) Shop China Manufacturer Supply High Purity MEBENDAZOLE CAS 31431-39-7-Detailed Image 2
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    2.3Other hazards which do not result in classification

    no data available

    SECTION 3: Composition/information on ingredients

    3.1Substances

    Chemical name Common names and synonyms CAS number EC number Concentration
    Mebendazole Mebendazole 31431-39-7 250-635-4 100%

    SECTION 4: First-aid measures

    4.1Description of necessary first-aid measures

    If inhaled

    Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

    Following skin contact

    Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

    Following eye contact

    Rinse with pure water for at least 15 minutes. Consult a doctor.

    Following ingestion

    Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

    4.2Most important symptoms/effects, acute and delayed

    SYMPTOMS: Symptoms of exposure to this compound may include headache, dizziness, gastrointestinal disturbances, pruritus, drowsiness, abnormalities in liver-function test, eosinophilia, lowered hemoglobin concentrations, leucopenia, hematuria and casts, cough, fever, glomerulonephritis, abdominal pain, diarrhea, nausea and vomiting. It may also cause allergic reactions, alopecia and reversible neutropenia. ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits very toxic fumes of NOx. (NTP, 1992)

    4.3Indication of immediate medical attention and special treatment needed, if necessary

    Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool . Cover skin burns with dry sterile dressings after decontamination . Poisons A and B

    SECTION 5: Fire-fighting measures

    5.1Suitable extinguishing media

    Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

    5.2Specific hazards arising from the chemical

    Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

    5.3Special protective actions for fire-fighters

    Wear self-contained breathing apparatus for firefighting if necessary.

    SECTION 6: Accidental release measures

    6.1Personal precautions, protective equipment and emergency procedures

    Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

    6.2Environmental precautions

    Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.

    6.3Methods and materials for containment and cleaning up

    Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

    SECTION 7: Handling and storage

    7.1Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    7.2Conditions for safe storage, including any incompatibilities

    Commercially available mebendazole chewable tablets should be stored at 15-25 deg C in well-closed containers .

    SECTION 8: Exposure controls/personal protection

    8.1Control parameters

    Occupational Exposure limit values

    no data available

    Biological limit values

    no data available

    8.2Appropriate engineering controls

    Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

    8.3Individual protection measures, such as personal protective equipment (PPE)

    Eye/face protection

    Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

    Skin protection

    Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

    Respiratory protection

    If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

    Thermal hazards

    no data available

    SECTION 9: Physical and chemical properties and safety characteristics

    Physical state

    PHYSICAL DESCRIPTION: White to slightly yellow powder. Pleasant taste. Practically water insoluble. (NTP, 1992)

    Colour

    Off-white amorphous powder

    Odour

    no data available

    Melting point/freezing point

    250°C(dec.)(lit.)

    Boiling point or initial boiling point and boiling range

    60°C/0.2mmHg(lit.)

    Flammability

    no data available

    Lower and upper explosion limit/flammability limit

    no data available

    Flash point

    76°C(lit.)

    Auto-ignition temperature

    no data available

    Decomposition temperature

    no data available

    pH

    no data available

    Kinematic viscosity

    no data available

    Solubility

    Practically insoluble (NTP, 1992)

    Partition coefficient n-octanol/water

    no data available

    Vapour pressure

    5.3X10-11 mm Hg at 25 deg C (est)

    Density and/or relative density

    1.388g/cm3

    Relative vapour density

    no data available

    Particle characteristics

    no data available

    SECTION 10: Stability and reactivity

    10.1Reactivity

    no data available

    10.2Chemical stability

    Tablets have expiration date of 3 yr following date of mfr

    10.3Possibility of hazardous reactions

    MEBENDAZOLE is a carbamate ester-amine. Amines behave as chemical bases. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.

    10.4Conditions to avoid

    no data available

    10.5Incompatible materials

    no data available

    10.6Hazardous decomposition products

    no data available

    SECTION 11: Toxicological information

    Acute toxicity

    • Oral: LD50 Sheep orally greater than 80 mg/kg
    • Inhalation: no data available
    • Dermal: no data available

    Skin corrosion/irritation

    no data available

    Serious eye damage/irritation

    no data available

    Respiratory or skin sensitization

    no data available

    Germ cell mutagenicity

    no data available

    Carcinogenicity

    no data available

    Reproductive toxicity

    no data available

    STOT-single exposure

    no data available

    STOT-repeated exposure

    no data available

    Aspiration hazard

    no data available

    SECTION 12: Ecological information

    12.1Toxicity

    • Toxicity to fish: no data available
    • Toxicity to daphnia and other aquatic invertebrates: no data available
    • Toxicity to algae: no data available
    • Toxicity to microorganisms: no data available

    12.2Persistence and degradability

    no data available

    12.3Bioaccumulative potential

    An estimated BCF of 83 was calculated for mebendazole(SRC), using a log Kow of 2.83(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is moderate(SRC), provided the compound is not metabolized by the organism(SRC).

    12.4Mobility in soil

    The Koc of mebendazole is estimated as 830(SRC), using a log Kow of 2.83(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that mebendazole is expected to have low mobility in soil.

    12.5Other adverse effects

    no data available

    SECTION 13: Disposal considerations

    13.1Disposal methods

    Product

    The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

    Contaminated packaging

    Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

    SECTION 14: Transport information

    14.1UN Number

    ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

    14.2UN Proper Shipping Name

    ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

    14.3Transport hazard class(es)

    ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

    14.4Packing group, if applicable

    ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

    14.5Environmental hazards

    ADR/RID: No IMDG: No IATA: No

    14.6Special precautions for user

    no data available

    14.7Transport in bulk according to IMO instruments

    no data available

    SECTION 15: Regulatory information

    15.1Safety, health and environmental regulations specific for the product in question

    Chemical name Common names and synonyms CAS number EC number
    Mebendazole Mebendazole 31431-39-7 250-635-4
    European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
    EC Inventory Listed.
    United States Toxic Substances Control Act (TSCA) Inventory Not Listed.
    China Catalog of Hazardous chemicals 2015 Not Listed.
    New Zealand Inventory of Chemicals (NZIoC) Listed.
    Philippines Inventory of Chemicals and Chemical Substances (PICCS) Not Listed.
    Vietnam National Chemical Inventory Listed.
    Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Not Listed.
    Korea Existing Chemicals List (KECL) Not Listed.

    SECTION 16: Other information

    Information on revision

    Creation Date July 15, 2019
    Revision Date July 15, 2019

    Abbreviations and acronyms

    • CAS: Chemical Abstracts Service
    • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
    • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
    • IMDG: International Maritime Dangerous Goods
    • IATA: International Air Transportation Association
    • TWA: Time Weighted Average
    • STEL: Short term exposure limit
    • LC50: Lethal Concentration 50%
    • LD50: Lethal Dose 50%
    • EC50: Effective Concentration 50%

    Pls input...

    Shop China Manufacturer Supply High Purity MEBENDAZOLE CAS 31431-39-7-Detailed Image 3

    Items Specifications
    Appearance White Powder

    Shop China Manufacturer Supply High Purity MEBENDAZOLE CAS 31431-39-7-Detailed Image 4Shop China Manufacturer Supply High Purity MEBENDAZOLE CAS 31431-39-7-Detailed Image 5Shop China Manufacturer Supply High Purity MEBENDAZOLE CAS 31431-39-7-Detailed Image 6Shop China Manufacturer Supply High Purity MEBENDAZOLE CAS 31431-39-7-Detailed Image 7

    Basic Info
    Product Name:

    Mebendazole

    Other Name:

    Carbamic acid,N-(6-benzoyl-1H-benzimidazol-2-yl)-,methyl ester;2-Benzimidazolecarbamic acid,5-benzoyl-,methyl ester;Carbamic acid,(5-benzoyl-1H-benzimidazol-2-yl)-,methyl ester;Mebendazole;Methyl 5-benzoyl-2-benzimidazolecarbamate;R 17635;Methyl 5-benzoyl-2-benzimidazolylcarbamate;(5-Benzoyl-1H-benzimidazol-2-yl)carbamic acid methyl ester;5-Benzoyl-2-benzimidazolecarbamic acid methyl ester;Pantelmin;Telmin;Vermox;Mebenvet;Ovitelmin;Besantin;NSC 184849;Verpanyl;Mebex;Equivurm Plus;Vermirax;Bantenol;Noverme;Lomper;Vermicidin;Zhihuanqing;Vermoxine;52776-90-6

    CAS No.:

    31431-39-7

    Molecular Formula:

    C16H13N3O3

    InChIKeys:

    InChIKey=OPXLLQIJSORQAM-UHFFFAOYSA-N

    Molecular Weight:

    295.29

    Exact Mass:

    295.29

    EC Number:

    250-635-4

    UNII:

    81G6I5V05I

    NSC Number:

    757838|184849

    DSSTox ID:

    DTXSID4040682

    NCI Thesaurus Code:

    C47595

    Color/Form:

    Off-white amorphous powder|Crystals from acetic acid and methanol

    ATC Code:

    P02CA01|P - Antiparasitic products, insecticides and repellents

    HScode:

    29339900

    Categories:

    Antiparasitics

    Characteristics
    PSA:

    84.1

    XLogP3:

    2.8

    Appearance:

    Mebendazole is a white to slightly yellow powder. Pleasant taste. Practically water insoluble. (NTP, 1992)

    Density:

    1.38 g/cm3

    Melting Point:

    288.5 °C

    Refractive Index:

    1.702

    Water Solubility:

    35.4mg/L(25 ºC)

    Storage Conditions:

    0-6°C

    Vapor Pressure:

    5.3X10-11 mm Hg at 25 deg C (est)

    Toxicity:

    LD50 orally: >80 mg/kg in sheep; >40 mg/kg in mice, rats and chickens (Van Gelder)

    Taste:

    NOT UNPLEASANT

    Henrys Law Constant:

    Henry's Law constant = 5.4X10-16 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa = 6.6 (double-bonded nitrogen) (est)

    Collision Cross Section:

    171.2 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|174.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with Waters Major Mix]|187.8 Ų [M+Na]+ [CCS Type: TW, Method: calibrated with Waters Major Mix]

    Experimental Properties:

    Hydroxyl radical reaction rate constant = 1.4X10-10 cu cm/molecule-sec at 25 °C (est)

    Air and Water Reactions:

    Insoluble in water.

    Reactive Group:

    Carbamates

    Reactivity Profile:

    MEBENDAZOLE is a carbamate ester-amine. Amines behave as chemical bases. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Commercially available mebendazole chewable tablets should be stored at 15-25 deg C in well-closed containers .

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Food additives,Pharmaceutical raw materials,Chemicals,Comestic raw materials

    Location:

    Room 501, Unit 6, No. 40, hushan road,Licang,Qingdao

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2017

    QINGDAO EASTCHEMSORCES TRADE LIMITED is a leading Manufactory supplier of Sorbitol, Citric acid, Sodium hypochlorite based in Qingdao, Shandong, China. With a commitment to quality and customer satisfaction, QINGDAO EASTCHEMSORCES TRADE LIMITED has become a trusted name in the industry. Our product line includes a range of high-quality Sorbitol, Citric acid, Sodium hypochlorite, which are available at competitive prices. QINGDAO EASTCHEMSORCES TRADE LIMITED has established itself as a reliable supplier of chemical products on the echemi.com.

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