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China Supplier Factory Direct Supply high quality Manufacturer Supply Top Quality CAS 446-86-6 Azathioprine Powder

Name: China Supplier Factory Direct Supply high quality Manufacturer Supply Top Quality CAS 446-86-6 Azathioprine Powder
Brand: TNJONE
SKU: pr2407121217
Price: 45 USD
Availability: InStock

Unit Price: Get Latest Price 

CAS No.:

446-86-6

Grade:

Azathioprine is used to prevent rejections of kidney or liver allografts, usually in conjunction with other therapies including corticosteroids, other immunosuppressants, and local radiation therapy. The administration protocol starts either at the time of transplantation or within the following two days.

Company Profile

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Shaanxi TNJONE Pharmaceutical Co., Ltd is a high-tech enterprise mainly engaged inthe development and sale of pharmaceutical chemical raw materials and relatedproducts.The company has advanced and perfect supporting system,forming advancedchemical synthesis technology, which can quickly meet the individual needs and serialdevelopment from suitable detection to industrial production.Qur business covers morethan 30 countries, most of customers from Europe, Southeast Asia and other countriesin the world, we can guarantee the quality and price. Our enterprise purpose is basedon the market, strengthen strength, take the road of scientific environmental protectionand sustainable development, rely on the country. The company has a strong financialstrength and a good business environment, can provide customers with quality,efficientand fast service.

Our Advantages

1.High quality and competitive price.
2.Free sample for your evaluation.
3.Promptly delivery by well-reputed shipping lines.
4.Trial order is available for testing after samples.
5.We will inform you all the information at every stage in advance.
6.Packaging can gear to buyers' special request.

Our factory

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How to order

Before ordering	Please send what items and what quantity you need
Send quotation	We will send you a quotation in detail with total
Payment ways chosen	Please choose one of the payment way you preferred. Our payment ways: City bank,BTC,Bank wire, Wise,Master Card , Tether
After payment	Please offer shipping address after payment for shipment.
Tracking	We will provide the tracking after goods sent.
Lead time	About 1-5 working days after payment
Shipping time	About 8-15 days door to door
After-sale service	Available always

Basic Info

Product Name:

Azathioprine

Other Name:

9H-Purine,6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-;Purine,6-[(1-methyl-4-nitroimidazol-5-yl)thio]-;1H-Purine,6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-;6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine;NSC 39084;Azathioprine;Azothioprine;Imuran;6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine;6-(1-Methyl-4-nitromidazol-5-ylthio)purine;Muran;BW 57-322;Imurel;Imurek;Azathioprin;Azanin;Azoran;Azamune;Azathropine;Azafor;Azasan;6165-04-4;11120-16-4;33609-91-5

CAS No.:

446-86-6

Molecular Formula:

C9H7N7O2S

InChIKeys:

InChIKey=LMEKQMALGUDUQG-UHFFFAOYSA-N

Molecular Weight:

277.27

Exact Mass:

277.26

EC Number:

207-175-4

UNII:

MRK240IY2L

NSC Number:

755900|39084

DSSTox ID:

DTXSID4020119

NCI Thesaurus Code:

C290

Color/Form:

Pale yellow crystals from 50% aq acetone

ATC Code:

L04AX01|L - Antineoplastic and immunomodulating agents

HScode:

2933990090

Categories:

Other Chemical Drugs

Characteristics

PSA:

143

XLogP3:

0.1

Appearance:

Azathioprine appears as pale yellow crystals or yellowish powder. Decomposes at 243-244°C. Used for the treatment of rheumatoid arthritis. A known carcinogen.

Density:

1.9±0.1 g/cm3

Melting Point:

243.5 °C

Boiling Point:

555.8°C at 760 mmHg

Flash Point:

368.5±31.5 °C

Refractive Index:

1.924

Water Solubility:

H2O: <0.1 g/100 mL at 23 ºC;soluble in Dichloromethane and dimethyl sulfoxide.

Storage Conditions:

Freezer

Vapor Pressure:

7.98E-12mmHg at 25°C

Toxicity:

Oral-rat LD50: 535 mg/kg; Oral-Mouse LD50: 1389 mg/kg

Flammability characteristics:

It can burn and produce toxic nitrogen and sulfur oxide fumes; side effects of patients after use: changes in liver function, excessive gastrointestinal movement, nausea, vomiting, diarrhea, increased body temperature, low blood pressure, low urine output, no urine

PKA:

7.87(at 25 °C)

Dissociation Constants:

7.87 (at 25 °C)|pKa = 8.2

Collision Cross Section:

155.1 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Experimental Properties:

Soly in water: 10 mg/ml /Sodium salt/

Air and Water Reactions:

Sensitive to oxidation in the air. Insoluble in water.

Reactive Group:

Amines, Phosphines, and Pyridines

Reactivity Profile:

AZATHIOPRINE may react exothermically with acids. Incompatible with isocyanates, peroxides, phenols, epoxides, anhydrides, and acid halides. Hydrolyzed by strongly basic solutions (NTP, 1992). May react with strong reducing agents to generate flammable gaseous hydrogen or hydrogen sulfide.

See More Azathioprine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

Germ cell mutagenicity, Category 1A

Carcinogenicity, Category 1A

Reproductive toxicity, Category 1A

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation H340 May cause genetic defects H350 May cause cancer H360 May damage fertility or the unborn child
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P203 Obtain, read and follow all safety instructions before use.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell. P318 IF exposed or concerned, get medical advice.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Storage of the constituted soln in the original vial and in plastic syringes (Jelco) at 20-25 deg C under fluorescent light resulted in no decomp or precipitation in 16 days. At 4 deg C in the dark, a visible precipitate formed after four days. Azathioprine sodium

See More Azathioprine Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,API,Vitamins,Food Additive

Location:
No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
5

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2019

Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.
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Name	Azathioprine
CAS NO.	446-86-6
purity	99%
Standard packing material	Bag/Box
Appearance	white power
Shelf Life	2Years
storage condition and solubility	Inert atmosphere,at 2-8°C;Sealed in dry,Store in freezer

B atch N o .	HF171121	Q uantity	8.5kgs
Mfg. Date	Nov. 21, 2017	Package	As required
R ep . D ate	Nov. 25, 2017	E xp . D ate	Nov. 20, 2019
I tems	S tandards		R esults
Appearance	White or off-white solid powder		Complies
I dentification	By IR		Complies
	By HPLC		Complies
Solubility	Soluble in DMF, sparingly soluble in THF, slightly soluble in methanol and acetonitrile, very sightly soluble in ethanol and dichloromethane, insoluble in water		Complies
Polymorphic Form	Polymorphic form 1		Complies
Melting Point	211ºC~216ºC		212.8ºC~214.9ºC
Water Content	≤ 0.50%		0.10%
H eavy M etals	≤ 20ppm		Complies
Residue on Ignition	≤ 0.20%		0.09%
R elat ed S ubstance	Any single impurity: ≤0.10%		0.06%
	Total Impurities: ≤1.00%		0.16%
Assay (on the anhydrous basis)	98.0%~102.0%		99.94%
Particle Size	D90: ≤100µm		Complies
Reference Standard	In-house Standard
Conclusion	The product complie d to In-house standard .
Storage	Preserve in tight,light-resistant containers in a cool place

China Supplier Factory Direct Supply high quality Manufacturer Supply Top Quality CAS 446-86-6 Azathioprine Powder

Product Description

Seller Information