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Pazopanib hydrochloride powder buy - large image1
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Pazopanib hydrochloride powder

2 Inquiries

Unit Price: Get Latest Price
CAS No.:

635702-64-6

Port:

any port of china

Packaging:

25kg/bag

Price valid (until):

2025-01-12

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

APIs,Veterinary,Cosmetic Ingredients,Peptides,intermediates,food ingredients

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Pazopanib hydrochloride is a multi-target tyrosine kinase inhibitor that inhibits angiogenesis and is used in the treatment of advanced renal cell carcinoma (RCC). Tyrosine kinases are the most common growth factor receptors, and most RCC patients experience hypoxia-induced factor (HIF)-mediated transcriptional activation due to VHL gene mutations and abnormal tumor growth. This leads to overexpression of VEGF, PDGF, EGF, and TGF-α, which activates the Raf/MEK/ERK and PI3K/Akt/mTOR pathways through receptor tyrosine kinase autophosphorylation. 

    Items Specifications






    Basic Info
    Product Name:

    Pazopanib hydrochloride

    Other Name:

    Benzenesulfonamide,5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-,hydrochloride (1:1);Benzenesulfonamide,5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-,monohydrochloride;Pazopanib hydrochloride;GW 786034B;5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide hydrochloride

    CAS No.:

    635702-64-6

    Molecular Formula:

    C21H23N7O2S.ClH

    InChIKeys:

    InChIKey=MQHIQUBXFFAOMK-UHFFFAOYSA-N

    Molecular Weight:

    473.987

    Exact Mass:

    473.140076

    EC Number:

    1308068-626-2

    Categories:

    Blood System Drugs

    Characteristics
    PSA:

    127

    XLogP3:

    5.79510

    Boiling Point:

    728.8ºC at 760 mmHg

    Flash Point:

    394.6ºC

    Water Solubility:

    In water, 3.3 mg/L at 25 deg C (est)

    Storage Conditions:

    Store at room temperature between 20 deg C and 25 deg C (68 deg F to 77 deg F); excursions permitted to 15 deg C to 30 deg C (59 deg F to 86 deg F).

    Vapor Pressure:

    3.21X10-14 mm Hg at 25 deg C (est)

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    APIs,Veterinary,Cosmetic Ingredients,Peptides,intermediates,food ingredients

    Location:

    T2-805,European and American Financial City,Cangqian Street,Yuhang District,Hangzhou,China.(zip code:311121)

    Payment Terms:

    TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    20

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    11-50

    Year of Establishment:

    2009

    Hangzhou Holypharm Biotech Co., Ltd was founded in Hangzhou in 2006. Over the decades, Holypharm has maintained sound development and rapid global expansion. Based on China and looking at the world, the Holypharm has become a leading professional health industry chain service group in China.

     

    Holypharm supplies different kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, intermediates, food additives, natural nutrition ingredients, feed additives, cosmetic additives, , medical devices, etc. Based on the deep strategic cooperation with Brightgene Pharmaceutical Company, and integrated production advantages, Holypharm's marketing network has spread over more than 40 countries and regions on five continents, providing professional service for global customers.

     

    With a commitment to quality and customer satisfaction, Holypharm has become a trusted name in the industry. Our strong product line includes like a range of high-quality tripeptide copper, (±)-Lipoic acid in cosmetics, Sameglutide Tirzepatide in the field of metabolism which are available at competitive prices. Holypharm has established itself as a reliable supplier of chemical products on the echemi.com.

     

    In the future, Holypharm will expand its business in the CDMO and OEM industry, connect the investment, R&D and production, and gradually become a integrated enterprise. Holypharm will stay true to the mission of serving the global health industry and helping create a win-win situation.


  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Russia

    Pazopanib hydrochloride

    100 KG Dec 10, 2024
    Pakistan

    Pazopanib hydrochloride

    1 KG May 23, 2025
    Post an enquiry for this product
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