Hot Selling Factory Wholesale High Purity Weight Loss Peptide Retatrutide 2381089-83-2

  Product Detail  

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• What is Retatrutide?

  Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

  Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

  In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

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• Retatrutide

  CAS#: 2381089-83-2

  Molecular Formula: C221H342N46O68

  Molecular Weight: 4731.33

  Sequence: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

  Appearance: White Powder

  Purity (HPLC): ≥99.0%

  Single Impurity (HPLC): ≤1.0%

  Sodium Content (HPLC): 5.0%-12.0%

  Moisture Content (Karl Fischer): ≤10.0%

  Peptide Content: ≥80.0%

  Storage: Store at 2-8 degrees Celsius in a dry and cool place.

  Packaging: 1g-1kg, plastic bottle

  Intended Use: For scientific research purposes

  Product Function:

  Helps slow food leaving your stomach
  Helps prevent your liver from making too much sugar
  Helps the pancreas produce more insul when your blood sugar levels are high
  Can help control blood glucose
  Can reduce hyperglycemia, especially after meals
  Can reduce fasting insul and fasting glucose
  Can reduce hemoglobin A1c
  Can decrease appetite and caloric intake, while inhibiting weight gain
  Has been shown to lower triglyceride levels and oxidative stress from high LDL
  Has been shown to help induce weight loss in obese patients with higher dosing
  Helps decrease leptin and increase leptin sensitivity
  Can increase the conversion of white fat to brown fat

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• Product Specification:                                                   
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• Items	Specifications
  Product Name	Retatrutide
  CAS No.	2381089-83-2
  Purity	>99.0%
  Molecular Formula	C187H291N45O5
  Appearance	White Lyophilized powder
  Application	Weight loss
  Storage	Cool Dry Place

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  Company Profile                                                            

    Changsha Duole Technology Co., Ltd was established in 2020 with strong research and development capabilities and superb synthesis technology, as well as advanced quality control measures.

    With synthetic biology platform technology as the core, it conducts innovative research and development, mainly engaged in the research and development of recombinantly expressed pharmaceutical peptides and proteins. Its products include innovative drugs, APIs, pharmaceutical and green synthetic industrial enzymes, functional peptides and protein products, etc.

    Its core team is composed of technical experts in the fields of pharmaceutical engineering, fermentation engineering and protein engineering. The company has built a 3,300-square-meter recombinant drug research and development center in Shibei, Yuelu District, Changsha City. It has a complete pharmaceutical engineering, preparation and quality research system and talent team, and has built a GMP workshop to meet the international market API supply and CDMO services.

    At present, our company has realized the industrialization of a variety of biosynthetic peptide products and has obtained cooperation orders from many well-known domestic and foreign pharmaceutical companies.