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Home > Active Pharmaceutical Ingredients > Circulatory System Drugs > ACT-132577 for Sale > high quality API Aprocitentan powder 99% for hypertension treatment
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high quality API Aprocitentan powder 99% for hypertension treatment

Unit Price: Get Latest Price
CAS No.:

1103522-45-7

Content:

99%

Port:

qingdao

Brand:

JF

Packaging:

Aluminium foil bag,25kg drum

Price valid (until):

2025-09-28

Company Type:
Trader
Location:
Hongkong, China
Qualification:
Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

  • Product Description

  • Seller Information

  • Description


    99% purity Aprocitentan New drugs for hypertension  


    Product Name: APROCITENTAN
    Synonyms: N-Despropyl Macitentan;Aprocitentan;5-(4-BROMOPHENYL)-4-[2-(5-BROMOPYRIMIDIN-2-YL)OXYETHOXY]-6-(SULFAMOYLAMINO)PYRIMIDINE;N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]sulfamide;APROCITENTAN; ACT-132577; ACT 132577; ACT132577; DESPROPYL MACITENTAN;Despropyl Macitentan;Macitentan N-Despropyl Impurity
    CAS: 1103522-45-7
    MF: C16H14Br2N6O4S
    MW: 546.19

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    APROCITENTAN

    Items Specifications
    color  White
     purity 99%

    APROCITENTAN function

    Aprocitentan (ACT-132577) is a sulfonamide small molecule oral drug that can target endothelin receptors A/B (ETA/B) and

    antagonize the binding of endothelin-1 to ETA/B. Aprocitentan is the first endothelin-1 receptor antagonist approved by the U.S.

    Food and Drug Administration (FDA) for the treatment of refractory hypertension.

    It has brought a new treatment method to patients with hypertension, especially those with refractory hypertension, and is of milestone significance.

    our Package

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    Basic Info
    Product Name:

    ACT-132577

    Other Name:

    ACT-132577;N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]sulfamide;N-Despropyl Macitentan;Aprocitentan;Despropyl Macitentan

    CAS No.:

    1103522-45-7

    Molecular Formula:

    C16H14Br2N6O4S

    InChIKeys:

    DKULOVKANLVDEA-UHFFFAOYSA-N

    Molecular Weight:

    546.19316

    Exact Mass:

    543.91600

    UNII:

    MZI81HV01P

    Characteristics
    PSA:

    150.59000

    XLogP3:

    4.38590

    Density:

    1.841±0.06 g/cm3(Predicted)

    Boiling Point:

    705.0±70.0 °C(Predicted)

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

    Location:

    Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $50 million-$100 million

    Total Employees:

    51-100

    Year of Establishment:

    2012

    We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

    In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

    Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

    "Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

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