Hot Sale High Quality Dextran (1kDa) (5kDa) (40kDa) Raw Power With Best Price

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Chemical Profile and Structural Characteristics

Dextran (CAS 9004-54-0) is a complex, branched polysaccharide composed predominantly of linear α-1,6 glycosidic linkages with varying degrees of branching via α-1,2, α-1,3, or α-1,4 linkages depending on the bacterial strain of origin. This high molecular weight polymer is biosynthesized from sucrose by specific lactic acid bacteria and presents as a white, amorphous powder that is readily soluble in water and formamide but insoluble in ethanol and other common organic solvents. The molecular weight distribution ranges broadly from 10,000 to over 2,000,000 Da, with the degree of branching and exact molecular architecture significantly influencing its physicochemical properties and biological behavior.

Functional Properties and Biological Interactions

The compound demonstrates exceptional hydrodynamic volume and solution viscosity relative to its molecular weight, forming random coil configurations in aqueous environments that generate significant osmotic activity. These properties enable its function as a plasma volume expander through colloidal osmotic effects while simultaneously modifying rheological characteristics of biological fluids. The extensive hydroxyl groups present on the glucose subunits provide multiple sites for chemical modification, cross-linking, and conjugation, while the overall molecular configuration allows for minimal metabolic utilization in mammals and limited recognition by the immune system when of appropriate molecular weight ranges.

Industrial and Pharmaceutical Applications

Dextran serves critical functions as a plasma volume expander in intravenous solutions for hypovolemic shock, with clinical preference for specific molecular weight fractions (typically 40,000-70,000 Da) that balance circulatory retention and renal clearance. The polymer finds extensive application in chromatographic media for size-exclusion and ion-exchange separations, as a cryoprotectant in biological preservation, and as a component in drug delivery systems for controlled release. Additional applications include its use as a viscosity modifier in food products, an anti-thrombotic coating for medical devices, and a starting material for the synthesis of specialty chemicals through chemical modification of hydroxyl groups.

Manufacturing Process and Quality Control

We produce dextran through controlled fermentation processes using selected bacterial strains, followed by precise fractionation methodologies to obtain specific molecular weight distributions tailored to application requirements. The manufacturing protocol incorporates multiple purification steps including precipitation, ultrafiltration, and chromatographic separation to remove proteins, nucleic acids, and low molecular weight saccharides. Quality control parameters rigorously monitor molecular weight distribution by size-exclusion chromatography with multi-angle light scattering detection, branching characteristics by enzymatic digestion and chromatographic analysis, and purity through assessment of residual fermentation components and microbial contaminants.

Regulatory Status and Safety Profile

Dextran holds approvals from major regulatory agencies worldwide for pharmaceutical, food, and biomedical applications, with specific classifications depending on molecular weight and intended use. The compound demonstrates an excellent safety profile when administered as appropriate molecular weight fractions, with rare anaphylactoid reactions occurring primarily with higher molecular weight forms. Regulatory specifications include stringent controls on molecular weight distribution, purity from pyrogens and bacterial contaminants, and comprehensive characterization of chemical and physical properties to ensure batch-to-batch consistency and product performance across diverse applications.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.