Product Detail  

1. Basic Information

• Product Name: Neomycin Sulfate
• CAS No.: 1405-10-3
• Molecular Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄ (typical trihydrate sulfate form)
• Molecular Weight: 908.88
• Type: Aminoglycoside Antibiotic
• Source: Fermented by Streptomyces fradiae, mixture of neomycin B and its stereoisomer neomycin C

2. Physical and Chemical Properties

• Appearance: White or off-white powder, odorless or almost odorless
• Solubility: Highly soluble in water, slightly soluble in ethanol, almost insoluble in acetone and ether
• Hygroscopicity: Hygroscopic, easily degraded in humid environment; high temperature accelerates degradation
• pH Value: 5.0-7.5 (0.10g/ml CO₂-free aqueous solution)

3. Quality Standards & Key Indicators

• Standards: Complies with ChP, USP, BP, WHO standards
• Potency: Not less than 600 IU/mg (on dry basis); high-quality raw materials up to 664 U/mg
• Purity: ≥98% (HPLC)
• Endotoxin: Not detected (meets pharmaceutical grade standards)

4. Antibacterial Mechanism & Spectrum

5. Applications

• Pharmaceutical Field: Oral use for intestinal infections, pre-colon surgery preparation, adjuvant treatment of hepatic coma; topical ophthalmic use for sensitive bacterial eye infections (conjunctivitis, dacryocystitis, etc.); topical skin use for skin infections.
• Veterinary Field: Used for bacterial infections in livestock and poultry.

6. Packaging & Storage

• Packaging: Raw materials: 25 billion/barrel (≈31.8kg), 1kg/aluminum foil bag; formulations: tablets, eye drops, ointments, soluble powders (see specific instructions).
• Storage: Store in a cool, dry and well-ventilated place, away from light and moisture; shelf life: 36 months for raw materials (under specified conditions).