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Sorafenib

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Unit Price: Get Latest Price
CAS No.:

284461-73-0

Grade:

medical grade

Content:

98%

Brand:

Jinlan

Packaging:

25kg/Cardboard Drum

Price valid (until):

2026-03-01

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Peptides,API,Intermediate

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Sorafenib (284461-73-0)


    • CAS Number: 284461-73-0
    • Chemical Name: 4-[4-[[4-Chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide
    • Molecular Formula: C₂₁H₁₆ClF₃N₄O₃
    • Molecular Weight: 464.83 g/mol
    • EINECS Number: 613-908-3
    • Related Categories: First-in-class Multikinase Inhibitor, Raf/VEGFR/PDGFR Inhibitor, Oral Small Molecule, Solid Tumor Therapeutic, Angiogenesis Inhibitor
    • Key Highlight: First oral multikinase inhibitor inhibiting tumor proliferation (Raf/MEK/ERK) and angiogenesis (VEGFR/PDGFR); approved for advanced HCC, RCC and differentiated thyroid carcinoma (DTC).

    Basic Info
    Product Name:

    Sorafenib

    Other Name:

    2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-;4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide;BAY 43-9006;Sorafenib;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea;Nevaxar

    CAS No.:

    284461-73-0

    Molecular Formula:

    C21H16ClF3N4O3

    InChIKeys:

    InChIKey=MLDQJTXFUGDVEO-UHFFFAOYSA-N

    Molecular Weight:

    464.825

    Exact Mass:

    464.82

    EC Number:

    608-209-4

    UNII:

    9ZOQ3TZI87

    NSC Number:

    747971

    DSSTox ID:

    DTXSID7041128

    NCI Thesaurus Code:

    C61948

    Color/Form:

    White solid

    ATC Code:

    L01EX02|L01XE05|L - Antineoplastic and immunomodulating agents

    HScode:

    29350090

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    92.35000

    XLogP3:

    4.1

    Appearance:

    White to off-white solid

    Density:

    1.5±0.1 g/cm3

    Melting Point:

    215 °C

    Boiling Point:

    523.3±50.0 °C at 760 mmHg

    Flash Point:

    270.3±30.1 °C

    Refractive Index:

    1.626

    Water Solubility:

    1.71e-03 g/L

    Storage Conditions:

    Store at 25 deg C (77 deg F); excursions permitted to 15-30 deg C (59-86 deg F)

    Vapor Pressure:

    4.76E-11mmHg at 25°C

    Vapor Density:

    4.11X10-14 mm Hg at 25 deg C (est)

    Henrys Law Constant:

    Henry's Law constant = 1.85X10-20 atm-cu m/mol at 25 °C (est)

    Experimental Properties:

    White to yellowish or brownish solid. Practically insoluble in aqueous media, slightly soluble in ethanol and soluble in PEG 400 /Sorafenib tosylate/

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 1B

    Reproductive toxicity, Additional category for effects on or via lactation

    Specific target organ toxicity – repeated exposure, Category 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H360 May damage fertility or the unborn child

    H362 May cause harm to breast-fed children

    H372 Causes damage to organs through prolonged or repeated exposure

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P263 Avoid contact during pregnancy and while nursing.

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P273 Avoid release to the environment.

    Response

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptides,API,Intermediate

    Location:

    Room 606, Building 1, Fu Yi Commercial Center, Shangcheng District, Hangzhou City, Zhejiang Province - 1

    Payment Terms:

    100% TT in advance

    Average lead Time:

    275

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    51-100

    Year of Establishment:

    2020

    Hangzhou Jinlan Pharm-Drugs Technology Co., Ltd (with its export company Hangzhou Royall Import & Export Co.,Ltd.) is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int' l Airport and Shanghai Pudong Int' l Airport, the transportation and production environment are excellent. JINLAN PHARMA mainly business includes: 1) API, Pharmaceutical Intermediates, CMO, CRO, CDMO and so on. 2) Pharmaceutical Equipment such as: Distilled Water Machinery, Mixer, Sterilizer and so on.

    JINLAN PHARM focus on:

    ■ Contrast Agent

    ■ Anti-COVID APIs

    ■ Respiratory System APIs

    ■ Anti-tumor & Anti-Cancer APIs

    ■ Anti-Diabetes APIs

    ■ Anti-HCV & Anti-HBV APIs

    ■ Anti-HIV APIs

    ■ Peptides

    ■ Pharmaceutical Intermediates

    ■ CMO, CRO, CDMO

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Sorafenib

    10 G Nov 14, 2023
    Post an enquiry for this product
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