Mazdutide CAS 2259884-03-0 99% High Purity Peptide API Lyophilized Powder Global Special Line Shipping

• Mechanism of Action:                                                

  The superior therapeutic efficacy of mazdutide stems from its synergistic, balanced activation of two distinct G protein-coupled receptors (GPCRs) that play central, non-redundant roles in whole-body metabolic homeostasis: the GLP-1 receptor and glucagon receptor. This dual-target mechanism distinguishes mazdutide from single-target GLP-1 receptor agonists (GLP-1RAs), the current standard of care for obesity and T2DM.

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  Safety and Tolerability Profile:                                  

  Across all completed clinical trials, mazdutide has exhibited a favorable, well-characterized, and predictable safety and tolerability profile, consistent with the known safety profile of the GLP-1RA drug class, with no new unexpected safety signals identified to date.

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Ongoing Research：                                                   

Beyond its approved indications for obesity and T2DM, mazdutide's dual GLP-1R/GCGR mechanism supports broad therapeutic potential in a range of metabolic and non-metabolic diseases, with active preclinical and clinical research exploring these expanded indications.

1.Non-Alcoholic Steatohepatitis (NASH)

2.Cardiovascular Outcomes

3.Diabetes-Associated Cognitive Dysfunction

4.Polycystic Ovary Syndrome (PCOS)

• Product Specification:                                                
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• Product Name	Mazdutide
  CAS	2259884-03-0
  Synonyms	IBI362, LY3305677, OXM-3
  Purity	>99.0%
  Molecular Weight	4563.06 Da
  Molecular Formula	C₂₁₀H₃₂₂N₄₆O₆₇
  Sequence	Ac‑Aib‑EGTFTSDYS‑KLDLLRRAQD‑FIEWLIKKGRS‑NH₂ (acylated peptide)
  Storage Stability	≤‑20 °C for 24 months

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Company Profile：                                                      

EnShi Technology Co., Ltd is a modern advanced enterprise specializing in production and exportation of APIs, Pharmaceutical intermediates, plant extracts etc. Our products are widely used in medicine, health care products, cosmetics, nutritional supplements and food additives areas. With years of experience in the pharmaceutical chemical and biosynthetic industries.It provides compliant, stable and cost-effective core raw materials as well as one-stop CDMO/CMO solutions for global pharmaceutical enterprises and innovative drug R&D institutions.