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MOTS-c|Premium in stock

113 Inquiries

Unit Price:

$120/UNIT FOB

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CAS No.:

1627580-64-6

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Brand:

Pharma;Conutrix

Packaging:

10 vials/box

Price valid (until):

2026-07-04

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Anhui Ruibang Trading Co., Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

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Product Description
Seller Information
Inquiry History

Description
Executive Summary

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a premium-grade, 16-amino-acid mitochondrial-derived peptide (MDP) currently in stock for research applications. This bioactive signaling molecule, encoded by the mitochondrial genome, functions as a potent metabolic regulator and exercise mimetic, activating the AMPK pathway to enhance cellular energy metabolism, insulin sensitivity, and mitochondrial biogenesis. Our premium MOTS-c formulation offers unmatched purity, stability, and consistency, making it the gold standard for cutting-edge research in metabolic health, aging, exercise physiology, and anti-aging therapeutics.

1. Product Overview & Identification

1.1 Basic Product Information

Product Name: MOTS-c (Human) Acetate (Premium Grade)

CAS Number: 1627583-67-3

Molecular Formula: C₈₅H₁₃₆N₂₄O₂₃S

Molecular Weight: 1,958.223 Da

Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

Form: Lyophilized (freeze-dried) white to off-white powder

Purity: ≥99.0% (HPLC & Mass Spectrometry verified, third-party tested)

Availability: Premium in stock, ready for immediate shipment

Intended Use: For laboratory research purposes only (not for human or veterinary use)

1.2 Premium Grade Differentiation

Our premium MOTS-c stands apart from standard research-grade peptides through:

Ultra-High Purity: ≥99.0% purity (vs. 95-98% for standard grades), minimizing contaminants that could skew experimental results

Stringent Manufacturing: Produced under cGMP-compliant conditions in ISO 9001 certified facilities

Advanced Purification: Multiple rounds of HPLC purification and rigorous quality control testing

Stability Optimization: Specialized lyophilization process preserving peptide integrity for extended shelf life

Complete Documentation: Full COA (Certificate of Analysis), HPLC, and MS reports provided with every batch

Batch Consistency: Strict process controls ensure identical performance across all production batches

2. Scientific Background & Discovery

2.1 Discovery & Classification

MOTS-c was first identified in 2015 by Dr. Chang and colleagues at the University of California, San Francisco, who discovered this 16-amino-acid peptide encoded within a short open reading frame of the mitochondrial 12S rRNA gene. As a mitochondrial-derived peptide (MDP), MOTS-c represents a novel class of signaling molecules that facilitate communication between mitochondria and the nucleus, earning it classification as a "mitokine".

2.2 Evolutionary Conservation

The amino acid sequence of MOTS-c, particularly the first 11 residues, is highly conserved across 14 mammalian species, including humans, mice, and primates, indicating its fundamental biological importance in metabolic regulation. This evolutionary stability suggests MOTS-c serves critical, evolutionarily preserved functions in cellular energy homeostasis.

2.3 Physiological Expression

Endogenous MOTS-c is naturally expressed in various tissues, with highest concentrations in skeletal muscle, heart, and liver. Circulating levels increase significantly with exercise (up to 11.9-fold in skeletal muscle and 1.6-fold in plasma) and decline with age, making it a key factor in age-related metabolic dysfunction and physical decline.

3. Mechanism of Action

3.1 Primary Signaling Pathway: AMPK Activation

MOTS-c exerts its biological effects primarily through activation of the AMP-activated protein kinase (AMPK) pathway, the master regulator of cellular energy balance. This activation occurs through a unique mechanism:

MOTS-c inhibits the folate cycle and de novo purine synthesis

This inhibition leads to accumulation of AICAR (5-aminoimidazole-4-carboxamide ribonucleotide)

AICAR directly activates AMPK, initiating a cascade of metabolic adaptations
Items Specifications

mots-c 10mg*10vials

mots-c 15mg*10vials

mots-c 20mg*10vials
Basic Info

Product Name:
MOTS-c

Other Name:
MOTS-c

CAS No.:
1627580-64-6

Molecular Formula:
C101H152N28O22S2 • C2HF3O2

InChIKeys:
WYTHCOXVWRKRAH-UHFFFAOYSA-N

Molecular Weight:
2174.6

Exact Mass:
2174.1110958

Categories:
Bulk Drug Intermediates

Characteristics

See More MOTS-c Properties 
Seller Information

Business Type:
Trader

Main Products:
Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

Location:
Hefei, Provincia de Anhui

Year of Establishment:
2026

Items	Specifications
mots-c	10mg*10vials
mots-c	15mg*10vials
mots-c	20mg*10vials

Inquiry History

113 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Mots-C CAS 1627580-64-6	5 G	Apr 26, 2026
United States	MOTS-c (Human) Acetate 98% Powder 1627580-64-6 Senwayer	1 G	Sep 7, 2023
United States	Bodygrowth Peptides CAS 1627580-64-6 MOTS-c (Human) Acetate peptides powder	1 G	Feb 23, 2026
Brazil	MOTS-c 10mg Peptide Raw Material High Purity	10 PCS	Feb 17, 2026
United States	MOTS-c (Human) Acetate peptides powder	1 G	Mar 12, 2026
United States	Mots-C	1 KG	Sep 12, 2025
Australia	MOTS-c 50mg	30 PCS	May 25, 2026
United States	Mots C	4000 MG	May 20, 2026
China	Mots-C	10000 MT	May 19, 2026
Brazil	most-C	1 KG	May 12, 2026
Canada	Mots-c	1 KG	Apr 23, 2026
Greece	MOTS-C	10 G	Apr 14, 2026
Pakistan	MOTS-C	10 PCS	Apr 6, 2026
United States	Mots-C	10 MT	Apr 4, 2026
United States	Mots-c	100 MG	Mar 29, 2026
United States	Mots-c	10 MT	Mar 24, 2026
Australia	Mots-c	40 MG	Mar 23, 2026
Portugal	MOTS-c	10	Mar 21, 2026
Brazil	MOTS-c	100 MG	Mar 2, 2026
Egypt	Mots-c	1 PCS	Feb 28, 2026

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MOTS-c|Premium in stock

Product Description

Seller Information

Inquiry History

Executive Summary

1. Product Overview & Identification

1.1 Basic Product Information

1.2 Premium Grade Differentiation

2. Scientific Background & Discovery

2.1 Discovery & Classification

2.2 Evolutionary Conservation

2.3 Physiological Expression

3. Mechanism of Action

3.1 Primary Signaling Pathway: AMPK Activation

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