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Coumarin 6

Coumarin 6 structure

CAS No:
38215-36-0
Formula:
C20H18N2O2S
Chemical Name:
Coumarin 6
Synonyms:
2H-1-Benzopyran-2-one,3-(2-benzothiazolyl)-7-(diethylamino)-;Coumarin,3-(2-benzothiazolyl)-7-(diethylamino)-;3-(2-Benzothiazolyl)-7-(diethylamino)-2H-1-benzopyran-2-one;Coumarin 6;Coumarin 540;3-(2-Benzothiazolyl-7-(diethylamino)coumarin;3-(2′-Benzothiazolyl)-7-N,N-diethylaminocoumarin;NSC 290432;3-(Benzothiazol-2-yl)-7-diethylamino-2H-benzopyran-2-one;NK 1858;3-Benzothiazol-2-yl-7-diethylamino-chromen-2-one;3-(1,3-Benzothiazol-2-yl)-7-(diethylamino)chromen-2-one;54576-82-8
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Description

Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems[1].

Coumarin 6 is a member of 7-aminocoumarins. It has a role as a fluorochrome.

Coumarin 6 Basic Attributes

Molecular Weight：

350.43

Exact Mass：

350.43

EC Number：

253-830-2

NSC Number：

290432

DSSTox ID：

DTXSID5068079

HScode：

29329990

Characteristics

PSA：

70.7

XLogP3：

4.91590

Appearance：

Orange Powder

Density：

1.311 g/cm3

Melting Point：

212 °C

Boiling Point：

570.1ºC at 760 mmHg

Flash Point：

298.6ºC

Refractive Index：

1.69

Water Solubility：

H2O: negligible soluble ;DMF: soluble

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

20/21/22-36/37/38-34

safety instructions：

22-24/25-37/39-26-45-36/37/39-27

Marks：

Xn,C

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents.

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (33.33%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 4 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

coumarin 6

Coumarin 6 Use and Manufacturing

Uses

Fluorescent dye which is widely used for staining polymer particles, but also organelles or materials used in medicine.

Manufacturing Info：

2H-1-Benzopyran-2-one, 3-(2-benzothiazolyl)-7-(diethylamino)-: ACTIVE

Computed Properties

Molecular Weight:350.4
XLogP3:4.9
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:350.10889899
Monoisotopic Mass:350.10889899
Topological Polar Surface Area:70.7
Heavy Atom Count:25
Complexity:534
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Phosphorus oxychloride

Ethyl cyanoacetate

Morpholine

Potassium hydroxide

Sodium hydroxide

Ethyl acetate

Ethanol

Acetic acid

Isopropanol

Dimethylformamide

1-Butanol

PETROLEUM ETHER

1,2-Dichlorobenzene

Recommended Suppliers of Coumarin 6

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

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Coumarin 6

CAS No.: 38215-36-0

Content: 99.00%

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