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2′-C-Methylguanosine

2′-C-Methylguanosine structure

2′-C-Methylguanosine 

structure
  • CAS No:

    374750-30-8

  • Formula:

    C11H15N5O5

  • Chemical Name:

    2′-C-Methylguanosine

  • Synonyms:

    Guanosine,2′-C-methyl-;2′-C-Methylguanosine;INZ 08032;INX 08032;2′-C-Methylguanosine

  • Categories:

    Biochemical Engineering  >  Nucleoside Drugs

2′-C-Methylguanosine Basic Attributes

297.27

297.27

609-435-6

DTXSID50333335

Characteristics

155

0.34

white to beige

2.0±0.1 g/cm3

733.1±70.0 °C at 760 mmHg

397.2±35.7 °C

1.860

H2O: soluble5mg/mL, clear (warmed)

-20°C

Safety Information

NONH for all modes of transport

3

2′-C-Methylguanosine Use and Manufacturing

2’C-β-Methyl Guanosine is an anti-HCV agent. 2’C-β-Methyl Guanosine is an intermediate in the synthesis of novel double prodrug INX-08189, a new clinical candidate for hepatitis C virus.

Computed Properties

Molecular Weight:297.27
XLogP3:-1.7
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:297.10731860
Monoisotopic Mass:297.10731860
Topological Polar Surface Area:155
Heavy Atom Count:21
Complexity:488
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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