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Cibenzoline succinate

Cibenzoline succinate structure

CAS No:
100678-32-8
Formula:
C18H18N2.C4H6O4
Chemical Name:
Cibenzoline succinate
Synonyms:
Butanedioic acid,compd. with 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole (1:1);1H-Imidazole,2-(2,2-diphenylcyclopropyl)-4,5-dihydro-,butanedioate (1:1);Cifenline succinate;Cibenzoline succinate (1:1);Cipralan;Exacor;Ro 22-7796/001;Cibenol;Cibenzoline succinate;2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate;85589-37-3

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Description

Cibenzoline succinate is a diarylmethane.

Cibenzoline succinate Basic Attributes

Molecular Weight：

380.44

Exact Mass：

380.17400

EC Number：

260-856-8

DSSTox ID：

DTXSID0047820

Characteristics

PSA：

XLogP3：

2.69450

Appearance：

white to off-white

Melting Point：

165 °C

Boiling Point：

449.2ºC at 760mmHg

Flash Point：

225.5ºC

Water Solubility：

H2O: ≥5mg/mL

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

RTECS Number：

EJ9960100

Marks：

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

MeSH：

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

MeSH Entry Terms：

2-(2,2-diphenylcyclopropyl)-2-imidazoline

Cibenzoline succinate Use and Manufacturing

Cardiac depressant (anti-arrhythmic).

Computed Properties

Molecular Weight:380.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:380.17360725
Monoisotopic Mass:380.17360725
Topological Polar Surface Area:99
Heavy Atom Count:28
Complexity:450
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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Guide of Cibenzoline succinate

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Learn More Other Chemicals

Cibenzoline succinate

SDS

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