Sodium metabisulfite
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Sodium metabisulfite
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CAS No:
7681-57-4
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Formula:
H2O5S2.2Na
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Chemical Name:
Sodium metabisulfite
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Synonyms:
Sodium metabisulfite, SO258.5% min;disodiummetabisulfite;disodiumpyrosulphite;fertisilo;metabisulfitedesodium;Sodiummetabisufite;SodiumMetabisulphiteAcs;SodiumMetabisulphiteExtraPure
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CAS No:
Description
Sodium metabisulfite (chemical formula: Na2S2O5) appears as a white crystalline or powder solid with a slight sulfur odor. It is toxic upon inhalation and can strongly irritate skin and tissue. It can be decomposed to release toxic oxide fumes of sulfur and sodium upon high temperature. It can be mixed with water to form a corrosive acid. It is generally used as disinfectant, antioxidant, and preservative agent as well as a laboratory reagent. As a kind of food additive, it can be used as a preservative and antioxidant in food. It can also be applied to the wine and beer making. Moreover, it can be used to sanitize the equipment of homebrew and winemaking as a cleaning agent. It also have various kinds of other applications, e.g. being applied to photography, as an excipients in some tablets, for water treatment, as a source of SO2 in wine, as a bactericide and as a bleaching reagent as well as reducing agent. It can be manufactured through the evaporation of a sodium bisulfite which has been saturated with sulfur dioxide. It should be warned that sodium metabisulfite has certain acute effects on the respiratory system, eyes and skin. In severe case, it can cause breathing difficulty and even pulmonary damage which finally leads to death. Therefore, effective protective measures and attention should be taken during the operation.sodium metabisulfite powder
Sodium metabisulfite is a white crystalline powder. Sulfur dioxide odor. It may be considered the anhydride of 2 molecules of sodium disulfite.
Sodium metabisulfite occurs as colorless, prismatic crystals or as a white to creamy-white crystalline powder that has the odor of sulfur dioxide and an acidic, saline taste. Sodium metabisulfite crystallizes from cold water as a hydrate containing seven water molecules.
ChEBI: An inorganic sodium salt composed of sodium and disulfite ions in a 2:1 ratio.
Sodium metabisulfite (MBS, Sodium disulfite) is an inorganic salt. It is the sodium salt of disulphurous (pyrosulfurous) acid. It is widely used in textile dyeing, photography and paper industry. It is also commonly added to various food products and wines as a preservative.
Sodium metabisulfite Basic Attributes
192.12
231-673-0
TSCA listed
White to slightly yellow
2832 10 00
Characteristics
1.48
>300 °C (lit.)
1.474
540 g/L (20 ºC)
LD50 orally in Rabbit: 1540 mg/kg LD50 dermal Rat > 2000 mg/kg
Non flammable
Sulphorous
3.5-5 (50g/l, H2O, 20℃)
Store at +5°C to +30°C.
Safety Information
III
1
Xn,Xi
26-39-46-36-16
UX8225000
On exposure to air and moisture, sodium metabisulfite is slowly oxidized to sodium sulfate with disintegration of the crystals. Addition of strong acids to the solid liberates sulfur dioxide.In water, sodium metabisulfite is immediately converted to sodium (Na+) and bisulfite (HSO3-) ions. Aqueous sodium metabisulfite solutions also decompose in air, especially on heating. Solutions that are to be sterilized by autoclaving should be filled into containers in which the air has been replaced with an inert gas, such as nitrogen. The addition of dextrose to aqueous sodium metabisulfite solutions results in a decrease in the stability of the metabisulfite.The bulk material should be stored in a well-closed container, protected from light, in a cool, dry place.
22-31-41-36/37/38-52
Sodium metabisulfite reacts with sympathomimetics and other drugs that are ortho- or para-hydroxybenzyl alcohol derivatives to form sulfonic acid derivatives possessing little or no pharmacological activity. The most important drugs subject to this inactivation are epinephrine (adrenaline) and its derivatives. In addition, sodium metabisulfite is incompatible with chloramphenicol owing to a more complex reaction; it also inactivates cisplatin in solution.It is incompatible with phenylmercuric acetate when autoclaved in eye drop preparations.Sodium metabisulfite may react with the rubber caps of multidose vials, which should therefore be pretreated with sodium metabisulfite solution.
3260
This agent is frequently used as a preservative in pharmaceutical products, in the bread-making industry as an antioxidant, and it can induce contact dermatitis. It can be used as a reducing agent in photography and caused dermatitis in a photographic technician, probably acting as an aggravating irritative factor. Sodium metabisulfite contains a certain amount of sodium sulfite and sodium sulfate.
Drug Information
Sodium metabisulphite is currently listed in Annex III Part B of Directive 95/2/EC as an authorised food additive. As such food labelling is required where sulphite residues exceed 10 mg/kg (ppm). This is labelled E223 with maximum permitted residues in crustacean products set at 150 mg/kg. However it is now accepted that sulphites, when present in foodstuffs, can cause allergic reactions in vulnerable persons and can constitute a danger to health (Collins-Williams, 1983). Metabisulphite is regarded as one causative agent of asthma attacks (Gunnison & Jacobsen, 1987). In accordance with this, EU Directive 2003/89/EC will make allergen labelling a requirement for all food stuffs produced in the European Community, which have been treated with sodium metabisulphite.Sodium metabisulfite typically found in consumer products should pose little a risk of symptoms due to skin or inhalation exposure since sodium metabisulfite is used in very low concentrations. Sodium metabisulfite can produce the following adverse health affects:Contact - Skin exposures can cause symptoms ranging from minor skin irritation or itching to redness and swelling. Eye exposure to sodium metabisulfite may result in redness, tearing or moderate eye irritation.Inhalation - The inhalation of sodium metabisulfite dusts can cause nose and throat irritation or coughing. Repeated or prolonged exposures may cause sore throat or nosebleeds. Inhalation may also cause severe respiratory reactions and aggravate asthma or other breathing diseases.Ingestion - The ingestion of sodium metabisulfite may cause irritation of the mouth and throat, nausea, vomiting and diarrhea.Other Effects - The International Agency for Research on Cancer (IARC) has not classified sodium metabisulfite as a carcinogen (cancer causing).
Sodium metabisulfite Use and Manufacturing
Sodium metabisulfite (SMBS, Sodium disulfite) is a white, granular solid sodium salt. an inorganic compound made up of sodium, sulfur, and oxygen, and used in many industries:in the pulp and paper industry, in the photographic industry and in the various other industries as a bleach or dechlorinator.Food Grade sodium metabisulfite may be used as a food preservative. It is also commonly added to various food products and wines as a preservative.Sodium metabisulfite can also be used in the manufacture of other chemicals, Used in production of cleaning agents, detergents, and soaps.It also acts as a corrosion inhibitor in oil and gas industry, as a bleaching agent in the production of coconut cream, as the source of sulfur dioxide and in the destruction of cyanide in commercial gold cyanidation processes.Gold mining industry: It is utilized in the precipitation of gold from auric acid as well as in the waste water treatment to remove hexavaent chromium as trivalent chromium by precipitation after reduction.Preservative in photo developer solutions, it is used in photography.Oxygen scavenge:it plays as an oxygen scavenger to eliminate the dissolved oxygen in wastewater and in pipes.Sodium metabisulfite may be used as an initiator during the cross-linking polymerization of polybutadiene in the cores of the vesicle membranes.It may be added as an antioxidant during the preparation of stock solutions of 6-hydroxydopamine in various studies.Dechlorination in municipal wastewater, pulp & paper, power, and textile water treatment plants.
Sodium Metabisulfite is a preservative and antioxidant that exists as crystals or powder having a sulfur dioxide odor. it is readily solu- ble in water. it is used in dried fruits to preserve flavor, color, and to inhibit undesirable microorganism growth. it prevents “black spots” due to oxidative deterioration in shrimp. it is used in maraschino cherries. it is found in lemon drinks as a preservative. see sulfur dioxide.
sodium metabisulfite is an anti-oxidant and reducing agent.
Pharmaceutic aid (antioxidant).
Sodium metabisulfite is prepared by saturating a solution of sodium hydroxide with sulfur dioxide and allowing crystallization to occur; hydrogen is passed through the solution to exclude air. Sodium metabisulfite may also be prepared by saturating a solution of sodium carbonate with sulfur dioxide and allowing crystallization to occur, or by thermally dehydrating sodium bisulfite.
Drug Function and Efficacy
Antioxidant and preservative that prevents oxidation of sensitive ingredients and inhibits microbial growth in aqueous formulations.
Recommended Suppliers of Sodium metabisulfite
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CN
2 YRS
Business licensed Certified factoryManufactory Supplier of sodium metabisulfite,Sodium bicarbonate
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