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(±)-Warfarin

(±)-Warfarin structure

CAS No:
81-81-2
Formula:
C19H16O4
Chemical Name:
(±)-Warfarin
Synonyms:
2H-1-Benzopyran-2-one,4-hydroxy-3-(3-oxo-1-phenylbutyl)-;Coumarin,3-(α-acetonylbenzyl)-4-hydroxy-;4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one;W.A.R.F. 42;3-(α-Acetonylbenzyl)-4-hydroxycoumarin;Compound 42;Coumafen;Coumafene;Coumefene;Dethmor;Kumader;3-(α-Phenyl-β-acetylethyl)-4-hydroxycoumarin;3-(1′-Phenyl-2′-acetylethyl)-4-hydroxycoumarin;Warfarin;Zoocoumarin;Kumadu;Rodafarin;1-(4′-Hydroxy-3′-coumarinyl)-1-phenyl-3-butanone;Athrombine-K;WARF compound 42;Ratron;4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one;Brumolin;Temus W;Vampirinip II;Ratron G;Vampirinip III;Kumatox;Coumaphen;Rodafarin C;(±)-Warfarin;(RS)-Warfarin;rac-Warfarin;DL-3-(α-Acetonylbenzyl)-4-hydroxycoumarin;(±)-Warfarin-alcohol;Co-Rax;Rodex;NSC 59813;Warf 5;Warfarin acid;Martefarin;Circuvit;5543-56-6;56573-89-8
Categories:
Active Pharmaceutical Ingredients > Blood System Drugs

Description

Warfarin(WARF42) is an anticoagulant drug normally used to prevent blood clot formation as well as migration.Target: OthersWarfarin is an anticoagulant normally used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body respectively. Warfarin and related 4-hydroxycoumarin-containing molecules decrease blood coagulation by inhibiting vitamin K epoxide reductase, an enzyme that recycles oxidized vita

(±)-Warfarin Basic Attributes

Molecular Weight：

308.33

Exact Mass：

308.33

EC Number：

201-377-6

HScode：

29322090

Characteristics

PSA：

63.6

XLogP3：

2.6

Appearance：

Colorless Crystalline

Density：

1.4

Melting Point：

161 °C

Boiling Point：

356°C

Flash Point：

2℃

Refractive Index：

1.635

Water Solubility：

Practically insoluble in water

Storage Conditions：

2-8°C

Vapor Pressure：

Vapour pressure, Pa at 20°C: (negligible)

Vapor Density：

Relative vapour density (air = 1): 10.6

Toxicity：

Oral-rat LD50: 1.6 mg/kg; Oral-Mouse LD50: 3 mg/kg

Flammability characteristics：

Flammable; highly toxic fumes can be emitted in the fire

Odor：

Odorless

Taste：

Tasteless

PKA：

5None

Safety Information

Packing level：

Hazard category：

6.1(a)

Transport codes：

UN 2811 6.1/PG 1

wgk germany：

hazard class code：

61-48/25-52/53-28-21-36-20/21/22-11

safety instructions：

53-45-61-52-36/37-28-26-16

RTECS Number：

GN4550000

Marks：

T,T+,Xn,F

Storage features：

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

Stability/Shelf Life：

After constitution, warfarin sodium is physically & chemically stable for only 4 hr at room temp.

Precautionary statement(s)：

Missing Phrase - N15.00950417-P201-P260-P280-P308 + P313

Hazard Statements：

H300-H312-H360-H372-H412

Toxicity

Toxicity class：

most toxic

(±)-Warfarin Use and Manufacturing

It is an anti-coagulant rodenticide used to kill rats and rats This product is an anticoagulant rodenticide, which is widely used all over the world. It is mainly used to kill domestic mice such as house mice, rattus norvegicus, as well as wild mice. The mode of action of Shashuling is to show anticoagulant effect after entering the mouse body, causing the mouse to bleed and cause death. Generally, the rodent control rate can reach more than 90% within three weeks after feeding. This product is also used as an oral anticoagulant. Called warfarin sodium, used to prevent and treat thromboembolic diseases.

Computed Properties

Molecular Weight:308.3
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:308.10485899
Monoisotopic Mass:308.10485899
Topological Polar Surface Area:63.6
Heavy Atom Count:23
Complexity:502
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Benzaldehyde

Chlorine dioxide

Toluene

2-Methoxypropene

Aspirin

Salicylic acid

Sulfuric acid

Thionyl chloride

Hydrocarbon waxes

Recommended Suppliers of (±)-Warfarin

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

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Warfarin

CAS No.: 81-81-2

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